Nucleophosmin (NPM)
B23; NPM1; Nucleolar Phosphoprotein B23,Numatrin; Nucleophosmin/Nucleoplasmin Family,Member 1
 HGNC 7910
 MGI 3647121
 RGD 3192
 UniProt P06748
 USCN C664
Nucleophosmin (NPM)
NPM1 is associated with nucleolar ribonucleoprotein structures and bind single-stranded nucleic acids. It may be involved in the assembly and/or transport of ribosome. Its regulation through SUMOylation (by SENP3 and SENP5) is another facet of the proteins's regulation and cellular functions. It is located in nucleolus, but it can be translocated to the nucleoplasm in case of serum starvation or treatment with anticancer drugs. The protein is phosphorylated.
Chromosomal aberrations involving NPM1 were found in patients with non-Hodgkin lymphoma, acute promyelocytic leukemia, myelodysplastic syndrome, and acute myelogenous leukemia.It has been found in the cytoplasm in patients with primary acute myelogenous leukemia.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC664Hu01 Recombinant Nucleophosmin (NPM) SDS-PAGE; WB; ELISA; IP.
RPC664Hu02 Recombinant Nucleophosmin (NPM) SDS-PAGE; WB; ELISA; IP.
Antibodies MAC664Hu22 Monoclonal Antibody to Nucleophosmin (NPM) WB, ICC, IHC-P, IHC-F, ELISA
PAC664Hu01 Polyclonal Antibody to Nucleophosmin (NPM) WB, ICC, IHC-P, IHC-F, ELISA
PAC664Hu02 Polyclonal Antibody to Nucleophosmin (NPM) WB, ICC, IHC-P, IHC-F, ELISA
PAC664Hu71 Biotin-Linked Antibody to Nucleophosmin (NPM) IHC;WB;ELISA
Assay Kits SEC664Hu ELISA Kit for Nucleophosmin (NPM) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC664Mu01 Recombinant Nucleophosmin (NPM) SDS-PAGE; WB; ELISA; IP.
RPC664Mu02 Recombinant Nucleophosmin (NPM) SDS-PAGE; WB; ELISA; IP.
Antibodies PAC664Mu01 Polyclonal Antibody to Nucleophosmin (NPM) WB, ICC, IHC-P, IHC-F, ELISA
PAC664Mu02 Polyclonal Antibody to Nucleophosmin (NPM) WB, ICC, IHC-P, IHC-F, ELISA
PAC664Mu71 Biotin-Linked Antibody to Nucleophosmin (NPM) IHC;WB;ELISA
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a