Nuclear Mitotic Apparatus Protein 1 (NUMA1)
NMP22; NUMA; Nuclear matrix protein-22; SP-H antigen
The NUMA protein was one of the first to be described as a cell cycle-related protein based on a distinct immunofluorescent staining pattern: in interphase, NUMA is present throughout the nucleus, and in mitosis, it localizes to the spindle apparatus (Lydersen and Pettijohn, 1980). Some patients with autoimmune disease have antibodies directed against the NUMA protein. The full-length NUMA cDNA (Compton et al., 1992; Yang et al., 1992) predicts a protein with a calculated molecular mass of about 237 kD, containing 2 globular domains separated by a coiled-coil domain of 1,485 amino acids. Wong et al. (2006) stated that the coiled-coil region of NUMA can form parallel coiled-coil dimers. By fluorescence in situ hybridization, Sparks et al. (1993) demonstrated that the NUMA1 gene is present in single copy and located on chromosome 11q13.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPC332Hu01 | Recombinant Nuclear Mitotic Apparatus Protein 1 (NUMA1) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPC332Hu02 | Recombinant Nuclear Mitotic Apparatus Protein 1 (NUMA1) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAC332Hu01 | Polyclonal Antibody to Nuclear Mitotic Apparatus Protein 1 (NUMA1) | WB; IHC; ICC; IP. |
MAC332Hu22 | Monoclonal Antibody to Nuclear Mitotic Apparatus Protein 1 (NUMA1) | WB; IHC; ICC; IP. | |
MAC332Hu21 | Monoclonal Antibody to Nuclear Mitotic Apparatus Protein 1 (NUMA1) | WB; IHC; ICC; IP. | |
PAC332Hu02 | Polyclonal Antibody to Nuclear Mitotic Apparatus Protein 1 (NUMA1) | WB; IHC; ICC; IP. | |
Assay Kits | SEC332Hu | ELISA Kit for Nuclear Mitotic Apparatus Protein 1 (NUMA1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Nuclear Mitotic Apparatus Protein 1 (NUMA1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Nuclear Mitotic Apparatus Protein 1 (NUMA1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Nuclear Mitotic Apparatus Protein 1 (NUMA1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Nuclear Mitotic Apparatus Protein 1 (NUMA1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Nuclear Mitotic Apparatus Protein 1 (NUMA1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Nuclear Mitotic Apparatus Protein 1 (NUMA1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Nuclear Mitotic Apparatus Protein 1 (NUMA1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Nuclear Mitotic Apparatus Protein 1 (NUMA1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Nuclear Mitotic Apparatus Protein 1 (NUMA1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Nuclear Mitotic Apparatus Protein 1 (NUMA1) | ELISA Kit Customized Service Offer |