Notch Homolog 3 (NOTCH3)

CADASIL; CASIL; Neurogenic locus notch homolog protein 3

NOTCH3 encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development.
Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPL147Hu01 Recombinant Notch Homolog 3 (NOTCH3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAL147Hu01 Polyclonal Antibody to Notch Homolog 3 (NOTCH3) WB; IHC; ICC; IP.
Assay Kits SEL147Hu ELISA Kit for Notch Homolog 3 (NOTCH3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPL147Mu01 Recombinant Notch Homolog 3 (NOTCH3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAL147Mu01 Polyclonal Antibody to Notch Homolog 3 (NOTCH3) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Notch Homolog 3 (NOTCH3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Notch Homolog 3 (NOTCH3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Notch Homolog 3 (NOTCH3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Notch Homolog 3 (NOTCH3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Notch Homolog 3 (NOTCH3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Notch Homolog 3 (NOTCH3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Notch Homolog 3 (NOTCH3) ELISA Kit Customized Service Offer