Nitric Oxide Synthase Interacting Protein (NOSIP)
CGI-25
CGI-25
-90330.jpg "Nitric Oxide Synthase Interacting Protein (NOSIP)")
Coimmunoprecipitation studies demonstrated the specific interaction of eNOS and NOSIP in vitro and in vivo, and complex formation was inhibited by a synthetic peptide of the caveolin-1 scaffolding domain. NO production was significantly reduced in eNOS-expressing CHO cells (CHO-eNOS) that transiently overexpressed NOSIP.
Stimulation with the calcium ionophore A23187 induced the reversible translocation of eNOS from the detergent-insoluble to the detergent-soluble fractions of CHO-eNOS, and this translocation was completely prevented by transient coexpression of NOSIP in CHO-eNOS. Immunofluorescence studies revealed a prominent plasma membrane staining for eNOS in CHO-eNOS that was abolished in the presence of NOSIP.
ELISA Kits(Enzyme-linked immunosorbent assay Kits)
CLIA Kits(Chemiluminescent immunoassay Kits)
| Catalog | Product Name | Organism | Manual |
|---|---|---|---|
| E90330Hu | ELISA Kit for Nitric Oxide Synthase Interacting Protein (NOSIP) | Homo sapiens (Human) | n/a |
| E90330Mu | ELISA Kit for Nitric Oxide Synthase Interacting Protein (NOSIP) | Mus musculus (Mouse) | n/a |
| E90330Ra | ELISA Kit for Nitric Oxide Synthase Interacting Protein (NOSIP) | Rattus norvegicus (Rat) | n/a |
| Catalog | Product Name | Organism | Manual |
|---|---|---|---|
| C90330Hu | CLIA Kit for Nitric Oxide Synthase Interacting Protein (NOSIP) | Homo sapiens (Human) | n/a |
| C90330Mu | CLIA Kit for Nitric Oxide Synthase Interacting Protein (NOSIP) | Mus musculus (Mouse) | n/a |
| C90330Ra | CLIA Kit for Nitric Oxide Synthase Interacting Protein (NOSIP) | Rattus norvegicus (Rat) | n/a |