Nexilin (NEXN)
NELIN; F Actin Binding Protein
 HGNC 29557
 MGI 1916060
 RGD 708354
 UniProt Q0ZGT2
 USCN H548
Nexilin (NEXN)
The name nexilin came from the Latin word nexilis, meaning 'bound together.' Full-length b-nexilin contains an N-terminal F-actin-binding domain (ABD), followed by a spacer, a coiled-coil region, a second ABD, and a long C-terminal tail. In comparison, s-nexilin lacks the N-terminal ABD and has an insertion in the C-terminal tail. Immunofluorescence microscopy revealed that both b-nexilin and s-nexilin colocalized with F-actin at focal contacts at the ends of stress fibers.
The nexilins did not localize to cell-cell junctions. Western blot analysis detected nexilin proteins with apparent molecular masses above 90 kD in rat brain, testis, and spleen and in cultured rodent fibroblasts. Neither protein was detected in liver, kidney, or epithelial cell lines.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH548Hu01 Recombinant Nexilin (NEXN) SDS-PAGE; WB; ELISA; IP.
Antibodies MAH548Hu21 Monoclonal Antibody to Nexilin (NEXN) WB, ICC, IHC-P, IHC-F, ELISA
PAH548Hu01 Polyclonal Antibody to Nexilin (NEXN) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEH548Hu ELISA Kit for Nexilin (NEXN) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH548Ra01 Recombinant Nexilin (NEXN) SDS-PAGE; WB; ELISA; IP.
Antibodies PAH548Ra01 Polyclonal Antibody to Nexilin (NEXN) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits n/a n/a n/a