Nexilin (NEXN)
NELIN; F Actin Binding Protein
The name nexilin came from the Latin word nexilis, meaning 'bound together.' Full-length b-nexilin contains an N-terminal F-actin-binding domain (ABD), followed by a spacer, a coiled-coil region, a second ABD, and a long C-terminal tail. In comparison, s-nexilin lacks the N-terminal ABD and has an insertion in the C-terminal tail. Immunofluorescence microscopy revealed that both b-nexilin and s-nexilin colocalized with F-actin at focal contacts at the ends of stress fibers.
The nexilins did not localize to cell-cell junctions. Western blot analysis detected nexilin proteins with apparent molecular masses above 90 kD in rat brain, testis, and spleen and in cultured rodent fibroblasts. Neither protein was detected in liver, kidney, or epithelial cell lines.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPH548Hu01 | Recombinant Nexilin (NEXN) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAH548Hu01 | Polyclonal Antibody to Nexilin (NEXN) | WB; IHC; ICC; IP. |
MAH548Hu21 | Monoclonal Antibody to Nexilin (NEXN) | WB; IHC; ICC; IP. | |
MAH548Hu22 | Monoclonal Antibody to Nexilin (NEXN) | WB; IHC; ICC; IP. | |
MAH548Hu23 | Monoclonal Antibody to Nexilin (NEXN) | WB; IHC; ICC; IP. | |
Assay Kits | SEH548Hu | ELISA Kit for Nexilin (NEXN) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPH548Mu01 | Recombinant Nexilin (NEXN) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAH548Mu01 | Polyclonal Antibody to Nexilin (NEXN) | WB; IHC; ICC; IP. |
Assay Kits | SEH548Mu | ELISA Kit for Nexilin (NEXN) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPH548Ra01 | Recombinant Nexilin (NEXN) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAH548Ra01 | Polyclonal Antibody to Nexilin (NEXN) | WB; IHC; ICC; IP. |
Assay Kits | SEH548Ra | ELISA Kit for Nexilin (NEXN) | Enzyme-linked immunosorbent assay for Antigen Detection. |