Neutrophil Activating Protein 3 (NAP3)
GRO1; CXCL1; GROa; GRO-A; MGSA-A; NAP3; SCYB1; Chemokine C-X-C-Motif Ligand 1; Melanoma Growth Stimulating Activity Alpha; Fibroblast Secretory Protein
CXCL1 is secreted by human melanoma cells, has mitogenic properties and is implicated in melanoma pathogenesis.CXCL1 is expressed by macrophages, neutrophils and epithelial cells,and has neutrophil chemoattractant activity.CXCL1 plays a role in spinal cord development by inhibiting the migration of oligodendrocyte precursors and is involved in the processes of angiogenesis, inflammation, wound healing, and tumorigenesis.
This chemokine elicits its effects by signaling through the chemokine receptor CXCR2.The gene for CXCL1 is located on human chromosome 4 amongst genes for other CXC chemokines.An initial study in mice showed evidence that CXCL1 decreased the severity of multiple sclerosis and may offer a neuro-protective function.
ELISA Kits(Enzyme-linked immunosorbent assay Kits)
CLIA Kits(Chemiluminescent immunoassay Kits)
| Catalog |
Product Name |
Organism |
Manual |
| C90041Hu | CLIA Kit for Neutrophil Activating Protein 3 (NAP3) | Homo sapiens (Human) | n/a |
| C90041Mu | CLIA Kit for Neutrophil Activating Protein 3 (NAP3) | Mus musculus (Mouse) | n/a |
| C90041Ra | CLIA Kit for Neutrophil Activating Protein 3 (NAP3) | Rattus norvegicus (Rat) | n/a |