Neutrophil Activating Protein 3 (NAP3)
GRO1; CXCL1; GROa; GRO-A; MGSA-A; NAP3; SCYB1; Chemokine C-X-C-Motif Ligand 1; Melanoma Growth Stimulating Activity Alpha; Fibroblast Secretory Protein
 HGNC 4602
 MGI 3037818
 OMIM 155730
 RGD 619869
 UCSC uc003hhh.1
 UniProt P09341
 USCN 90041
Neutrophil Activating Protein 3 (NAP3)
CXCL1 is secreted by human melanoma cells, has mitogenic properties and is implicated in melanoma pathogenesis.CXCL1 is expressed by macrophages, neutrophils and epithelial cells,and has neutrophil chemoattractant activity.CXCL1 plays a role in spinal cord development by inhibiting the migration of oligodendrocyte precursors and is involved in the processes of angiogenesis, inflammation, wound healing, and tumorigenesis.
This chemokine elicits its effects by signaling through the chemokine receptor CXCR2.The gene for CXCL1 is located on human chromosome 4 amongst genes for other CXC chemokines.An initial study in mice showed evidence that CXCL1 decreased the severity of multiple sclerosis and may offer a neuro-protective function.
 ELISA Kits(Enzyme-linked immunosorbent assay Kits)
Catalog Product Name Organism Manual
E90041HuELISA Kit for Neutrophil Activating Protein 3 (NAP3)Homo sapiens (Human)  PDF
E90041MuELISA Kit for Neutrophil Activating Protein 3 (NAP3)Mus musculus (Mouse)  PDF
E90041RaELISA Kit for Neutrophil Activating Protein 3 (NAP3)Rattus norvegicus (Rat)  PDF
 CLIA Kits(Chemiluminescent immunoassay Kits)
Catalog Product Name Organism Manual
C90041HuCLIA Kit for Neutrophil Activating Protein 3 (NAP3)Homo sapiens (Human)  n/a
C90041MuCLIA Kit for Neutrophil Activating Protein 3 (NAP3)Mus musculus (Mouse)  n/a
C90041RaCLIA Kit for Neutrophil Activating Protein 3 (NAP3)Rattus norvegicus (Rat)  n/a