Neutrophil Cytosolic Factor 2 (NCF2)
NOXA2; P67-PHOX; p67phox; 65kDa, Chronic Granulomatous Disease,Autosomal 2; NADPH Oxidase Activator 2
NOXA2; P67-PHOX; p67phox; 65kDa, Chronic Granulomatous Disease,Autosomal 2; NADPH Oxidase Activator 2
-90300.jpg "Neutrophil Cytosolic Factor 2 (NCF2)")
Neutrophil cytosol factor 2 is the 67-kilodalton cytosolic subunit of the multi-protein complex known as NADPH oxidase found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease.
Using neutrophils from a patient with p67-deficient CGD, Okamura et al. (1990) confirmed that the p67 protein functions in the respiratory burst mediated by NADPH oxidase and that p67 may be complexed to p47-phox (NCF1) while it participates in oxidase activation.
ELISA Kits(Enzyme-linked immunosorbent assay Kits)
CLIA Kits(Chemiluminescent immunoassay Kits)
| Catalog | Product Name | Organism | Manual |
|---|---|---|---|
| E90300Hu | ELISA Kit for Neutrophil Cytosolic Factor 2 (NCF2) | Homo sapiens (Human) | n/a |
| E90300Mu | ELISA Kit for Neutrophil Cytosolic Factor 2 (NCF2) | Mus musculus (Mouse) | n/a |
| E90300Ra | ELISA Kit for Neutrophil Cytosolic Factor 2 (NCF2) | Rattus norvegicus (Rat) | n/a |
| Catalog | Product Name | Organism | Manual |
|---|---|---|---|
| C90300Hu | CLIA Kit for Neutrophil Cytosolic Factor 2 (NCF2) | Homo sapiens (Human) | n/a |
| C90300Mu | CLIA Kit for Neutrophil Cytosolic Factor 2 (NCF2) | Mus musculus (Mouse) | n/a |
| C90300Ra | CLIA Kit for Neutrophil Cytosolic Factor 2 (NCF2) | Rattus norvegicus (Rat) | n/a |