Neutrophil Cytosolic Factor 2 (NCF2)
NOXA2; p67phox; 65kDa, Chronic Granulomatous Disease,Autosomal 2; NADPH Oxidase Activator 2; 67 kDa neutrophil oxidase factor; Neutrophil NADPH oxidase factor 2
Neutrophil cytosol factor 2 is the 67-kilodalton cytosolic subunit of the multi-protein complex known as NADPH oxidase found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease.
Using neutrophils from a patient with p67-deficient CGD, Okamura et al. (1990) confirmed that the p67 protein functions in the respiratory burst mediated by NADPH oxidase and that p67 may be complexed to p47-phox (NCF1) while it participates in oxidase activation.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA300Hu01 | Recombinant Neutrophil Cytosolic Factor 2 (NCF2) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA300Hu01 | Polyclonal Antibody to Neutrophil Cytosolic Factor 2 (NCF2) | WB; IHC; ICC; IP. |
Assay Kits | SEA300Hu | ELISA Kit for Neutrophil Cytosolic Factor 2 (NCF2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA300Mu01 | Recombinant Neutrophil Cytosolic Factor 2 (NCF2) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA300Mu01 | Polyclonal Antibody to Neutrophil Cytosolic Factor 2 (NCF2) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for Neutrophil Cytosolic Factor 2 (NCF2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Neutrophil Cytosolic Factor 2 (NCF2) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Neutrophil Cytosolic Factor 2 (NCF2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Neutrophil Cytosolic Factor 2 (NCF2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Neutrophil Cytosolic Factor 2 (NCF2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Neutrophil Cytosolic Factor 2 (NCF2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Neutrophil Cytosolic Factor 2 (NCF2) | ELISA Kit Customized Service Offer |