Neutrophil Cytosolic Factor 2 (NCF2)
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NOXA2; P67-PHOX; p67phox; 65kDa, Chronic Granulomatous Disease,Autosomal 2; NADPH Oxidase Activator 2
 HGNC 7661
 MGI 97284
 PubMed 24163247
 RGD 1309424
 UniProt P19878
 USCN A300
 Wiki NCF2
Neutrophil Cytosolic Factor 2 (NCF2)
Neutrophil cytosol factor 2 is the 67-kilodalton cytosolic subunit of the multi-protein complex known as NADPH oxidase found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease.
Using neutrophils from a patient with p67-deficient CGD, Okamura et al. (1990) confirmed that the p67 protein functions in the respiratory burst mediated by NADPH oxidase and that p67 may be complexed to p47-phox (NCF1) while it participates in oxidase activation.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA300Hu01 Recombinant Neutrophil Cytosolic Factor 2 (NCF2) SDS-PAGE; WB; ELISA; IP.
Antibodies PAA300Hu01 Polyclonal Antibody to Neutrophil Cytosolic Factor 2 (NCF2) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits n/a n/a n/a
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA300Mu01 Recombinant Neutrophil Cytosolic Factor 2 (NCF2) SDS-PAGE; WB; ELISA; IP.
Antibodies PAA300Mu01 Polyclonal Antibody to Neutrophil Cytosolic Factor 2 (NCF2) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a