Neurotrophic Tyrosine Kinase Receptor Type 1 (NTRK1)
MTC; TRK1; TRK-A; P140-TrkA; High Affinity Nerve Growth Factor Receptor; TRK1 Transforming Tyrosine Kinase Protein; Tropomyosin-related kinase A; Tyrosine kinase receptor
High affinity nerve growth factor receptor is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself (autophosphorylation) and members of the MAPK pathway.
The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain with anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.TrkA is part of a sub-family of protein kinases which includes TrkB and TrkC.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPC182Hu01 | Recombinant Neurotrophic Tyrosine Kinase Receptor Type 1 (NTRK1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAC182Hu21 | Monoclonal Antibody to Neurotrophic Tyrosine Kinase Receptor Type 1 (NTRK1) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for Neurotrophic Tyrosine Kinase Receptor Type 1 (NTRK1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Neurotrophic Tyrosine Kinase Receptor Type 1 (NTRK1) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Neurotrophic Tyrosine Kinase Receptor Type 1 (NTRK1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Neurotrophic Tyrosine Kinase Receptor Type 1 (NTRK1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Neurotrophic Tyrosine Kinase Receptor Type 1 (NTRK1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Neurotrophic Tyrosine Kinase Receptor Type 1 (NTRK1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Neurotrophic Tyrosine Kinase Receptor Type 1 (NTRK1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Neurotrophic Tyrosine Kinase Receptor Type 1 (NTRK1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Neurotrophic Tyrosine Kinase Receptor Type 1 (NTRK1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Neurotrophic Tyrosine Kinase Receptor Type 1 (NTRK1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Neurotrophic Tyrosine Kinase Receptor Type 1 (NTRK1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Neurotrophic Tyrosine Kinase Receptor Type 1 (NTRK1) | ELISA Kit Customized Service Offer |