Neurotrophic Tyrosine Kinase Receptor Type 1 (NTRK1)
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MTC; TRK; TRK1; TRK-A; P140-TrkA; High Affinity Nerve Growth Factor Receptor; TRK1 Transforming Tyrosine Kinase Protein
 HGNC 8031
 MGI 97383
 PubMed 10982191
 RGD 620144
 UniProt P04629
 USCN C182
 Wiki NTRK1
Neurotrophic Tyrosine Kinase Receptor Type 1 (NTRK1)
High affinity nerve growth factor receptor is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself (autophosphorylation) and members of the MAPK pathway.
The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain with anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.TrkA is part of a sub-family of protein kinases which includes TrkB and TrkC.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a