Neurofibromin 2 (NF2)
[ Edit ]
ACN; BANF; SCH; Merlin; Bilateral Acoustic Neuroma; Schwannomin; Schwannomerlin; Moesin-Ezrin-Radixin-Like Protein
 HGNC 7773
 MGI 97307
 PubMed 11809806
 RGD 3169
 UniProt P35240
 USCN B946
 Wiki NF2
Neurofibromin 2 (NF2)
Merlin is a cytoskeletal protein. In humans, it is a tumor suppressor protein involved in Neurofibromatosis type II.Sequence data reveal its similarity to the ERM protein family.The name "merlin" is an acronym for "Moesin-Ezrin-Radixin-Like Protein". Human merlin is coded by the gene NF2 in Chromosome 22. Mouse merlin gene is located on the chromosome 11 and rat merlin gene on the chromosome 17. Fruit fly merlin gene (symbol Mer) is located on chromosome 1 and shares 58% similarity to its human homologue. Other merlin-like genes are known from a wide range of animals, and the derivation of merlin is thought to be in early metazoa. Merlin is a member of the ERM family of proteins including ezrin, moesin, and radixin, which are in the protein 4.1 superfamily of proteins.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB946Hu01 Recombinant Neurofibromin 2 (NF2) SDS-PAGE; WB; ELISA; IP.
Antibodies MAB946Hu22 Monoclonal Antibody to Neurofibromin 2 (NF2) WB, ICC, IHC-P, IHC-F, ELISA
PAB946Hu01 Polyclonal Antibody to Neurofibromin 2 (NF2) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEB946Hu ELISA Kit for Neurofibromin 2 (NF2) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB946Mu01 Recombinant Neurofibromin 2 (NF2) SDS-PAGE; WB; ELISA; IP.
Antibodies PAB946Mu01 Polyclonal Antibody to Neurofibromin 2 (NF2) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a