Myosin Binding Protein C, Cardiac (MYBPC3)
MYBPC-3; FHC; CMH4; MYBP-C; C-protein, cardiac muscle isoform
MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle.
MYBPC gene is linked to CMH4 and demonstrated a splice donor mutationin 1 family with familial hypertrophic cardiomyopathy and a duplication mutation in a second. Both mutations were predicted to disrupt the high-affinity, C-terminal myosin-binding domain of cardiac MyBP-C. Again, findings demonstrated that as in the case of the 3 forms that had been defined in molecular terms previously, familial hypertrophic cardiomyopathy is a disease of the sarcomere.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPD016Hu01 | Recombinant Myosin Binding Protein C, Cardiac (MYBPC3) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAD016Hu01 | Polyclonal Antibody to Myosin Binding Protein C, Cardiac (MYBPC3) | WB; IHC; ICC; IP. |
MAD016Hu21 | Monoclonal Antibody to Myosin Binding Protein C, Cardiac (MYBPC3) | WB; IHC; ICC; IP. | |
Assay Kits | SED016Hu | ELISA Kit for Myosin Binding Protein C, Cardiac (MYBPC3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Myosin Binding Protein C, Cardiac (MYBPC3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Myosin Binding Protein C, Cardiac (MYBPC3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Myosin Binding Protein C, Cardiac (MYBPC3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Myosin Binding Protein C, Cardiac (MYBPC3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Myosin Binding Protein C, Cardiac (MYBPC3) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Myosin Binding Protein C, Cardiac (MYBPC3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Myosin Binding Protein C, Cardiac (MYBPC3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Myosin Binding Protein C, Cardiac (MYBPC3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Myosin Binding Protein C, Cardiac (MYBPC3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Myosin Binding Protein C, Cardiac (MYBPC3) | ELISA Kit Customized Service Offer |