Mothers Against Decapentaplegic Homolog 4 (Smad4)
DPC4; JIP; MADH4
 HGNC 6770
 MGI 894293
 PubMed 12821112
 RGD 3033
 UniProt Q13485
 USCN B925
 Wiki SMAD4
Mothers Against Decapentaplegic Homolog 4 (Smad4)
SMAD4 is a 552 amino acid protein involved in cell signaling. It belongs to the Darfwin family of proteins which modulate members of the TGFβ protein superfamily. It binds receptor regulated SMADs such as SMAD1 or SMAD2 and forms a complex that binds to DNA and serves as a transcription factor. It is the only known mammalian coSMAD. It is a homolog of the Drosophila protein: "Mothers against decapentaplegic".
The SMAD proteins are homologs of both the drosophila protein, mothers against decapentaplegic (MAD) and the C. elegans protein SMA. The name is a combination of the two. During Drosophila research, it was found that a mutation in the gene, MAD, in the mother, repressed the gene, decapentaplegic, in the embryo.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB925Hu01 Recombinant Mothers Against Decapentaplegic Homolog 4 (Smad4) SDS-PAGE; WB; ELISA; IP.
Antibodies MAB925Hu22 Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 4 (Smad4) WB, ICC, IHC-P, IHC-F, ELISA
PAB925Hu01 Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 4 (Smad4) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEB925Hu ELISA Kit for Mothers Against Decapentaplegic Homolog 4 (Smad4) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB925Mu01 Recombinant Mothers Against Decapentaplegic Homolog 4 (Smad4) SDS-PAGE; WB; ELISA; IP.
Antibodies PAB925Mu01 Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 4 (Smad4) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a