Mineralocorticoid Receptor (MR)
NR3C2; MLR; MCR; Aldosterone Receptor; Nuclear Receptor Subfamily 3 Group C Member 2
The mineralocorticoid receptor is a receptor with high affinity for mineralocorticoids. It belongs to the steroid hormone receptor family where the ligand diffuses into cells, interacts with the receptor and results in a signal transduction affecting specific gene expression in the nucleus. The gene for the NR3C2 encodes for the 107 kDa MR protein. MR is expressed in many tissues, such as the kidney, colon, heart, central nervous system (hippocampus), brown adipose tissue and sweat glands. In epithelial tissues, its activation leads to the expression of proteins regulating ionic and water transports resulting in the reabsoprtion of sodium, and as a consequence an increase in extracellular volume, increase in blood pressure, and an excretion of potassium to maintain a normal salt concentration in the body.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA464Hu01 | Recombinant Mineralocorticoid Receptor (MR) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA464Hu01 | Polyclonal Antibody to Mineralocorticoid Receptor (MR) | WB; IHC; ICC; IP. |
MAA464Hu22 | Monoclonal Antibody to Mineralocorticoid Receptor (MR) | WB; IHC; ICC; IP. | |
Assay Kits | SEA464Hu | ELISA Kit for Mineralocorticoid Receptor (MR) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Mineralocorticoid Receptor (MR) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Mineralocorticoid Receptor (MR) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Mineralocorticoid Receptor (MR) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Mineralocorticoid Receptor (MR) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Mineralocorticoid Receptor (MR) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA464Ra01 | Recombinant Mineralocorticoid Receptor (MR) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA464Ra01 | Polyclonal Antibody to Mineralocorticoid Receptor (MR) | WB; IHC; ICC; IP. |
MAA464Ra21 | Monoclonal Antibody to Mineralocorticoid Receptor (MR) | WB; IHC; ICC; IP. | |
Assay Kits | SEA464Ra | ELISA Kit for Mineralocorticoid Receptor (MR) | Enzyme-linked immunosorbent assay for Antigen Detection. |