Melanophilin (MLPH)
l1Rk3; l(1)-3Rk; Slac-2a; ln; Exophilin-3; Slp homolog lacking C2 domains a; Synaptotagmin-like protein 2a
Melanophilin encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin.
A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Melanophilin (MLPH) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Melanophilin (MLPH) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Melanophilin (MLPH) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Melanophilin (MLPH) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Melanophilin (MLPH) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Melanophilin (MLPH) | Recombinant Protein Customized Service Offer |
Antibodies | PAH637Mu01 | Polyclonal Antibody to Melanophilin (MLPH) | WB; IHC; ICC; IP. |
LAH637Mu71 | Biotin-Linked Polyclonal Antibody to Melanophilin (MLPH) | WB; IHC; ICC. | |
Assay Kits | n/a | CLIA Kit for Melanophilin (MLPH) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Melanophilin (MLPH) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Melanophilin (MLPH) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Melanophilin (MLPH) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Melanophilin (MLPH) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Melanophilin (MLPH) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Melanophilin (MLPH) | ELISA Kit Customized Service Offer |