Matrix Metalloproteinase 13(MMP13)
CLG3; Collagenase 3
MMP-13 has been proposed to participate in aggrecan degradation associated with osteoarthritis and cleavage of type II collagen in osteoarthritic cartilage explants and in tumor progression and metastasis . In addition, it can cleave type I, III, IV, IX, X and XIV collagens and fibronectin. MMP-13 is likely to play a crucial role in the modulation of extracellular matrix degradation and cell-matrix interactions .MMP-13 is expressed by several metastatic tumors including breast carcinomas, chondrosarcomas, head and neck carcinomas, and in degenerative bone diseases including rheumatoid arthritis. Wild type and mutant p53, a tumor suppressor gene, differentially regulate MMP-13 gene expression . Members of the activator protein-1 and core-binding factor families increase MMP-13 promoter activity in normal, differentiating osteoblasts .
ELISA Kits(Enzyme-linked immunosorbent assay Kits)
Antibodies
| Catalog |
Product Name |
Species |
Packing |
Price |
Manual |
| A90099Hu | Antibody to Human Matrix Metalloproteinase 13(MMP13) | Human | n/a | n/a | n/a |
| A90099Mu | Antibody to Mouse Matrix Metalloproteinase 13(MMP13) | Mouse | n/a | n/a | n/a |
| A90099Ra | Antibody to Rat Matrix Metalloproteinase 13(MMP13) | Rat | n/a | n/a | n/a |
| A90099Rb | Antibody to Rabbit Matrix Metalloproteinase 13(MMP13) | Rabbit | n/a | n/a | n/a |
| A90099Ca | Antibody to Canine Matrix Metalloproteinase 13(MMP13) | Canine | n/a | n/a | n/a |
| A90099Po | Antibody to Porcine Matrix Metalloproteinase 13(MMP13) | Porcine | n/a | n/a | n/a |
| A90099Bo | Antibody to Bovine Matrix Metalloproteinase 13(MMP13) | Bovine | n/a | n/a | n/a |
| A90099Cp | Antibody to Caprine Matrix Metalloproteinase 13(MMP13) | Caprine | n/a | n/a | n/a |
| A90099Eq | Antibody to Equine Matrix Metalloproteinase 13(MMP13) | Equine | n/a | n/a | n/a |
| A90099Ga | Antibody to Gallinaceous Matrix Metalloproteinase 13(MMP13) | Gallinaceous | n/a | n/a | n/a |
CLIA Kits(Chemiluminescent immunoassay Kits)
| Catalog |
Product Name |
Species |
Packing |
Price |
Manual |
| C90099Hu | CLIA Kit for Human Matrix Metalloproteinase 13(MMP13) | Human | n/a | n/a | n/a |
| C90099Mu | CLIA Kit for Mouse Matrix Metalloproteinase 13(MMP13) | Mouse | n/a | n/a | n/a |
| C90099Ra | CLIA Kit for Rat Matrix Metalloproteinase 13(MMP13) | Rat | n/a | n/a | n/a |
| C90099Rb | CLIA Kit for Rabbit Matrix Metalloproteinase 13(MMP13) | Rabbit | n/a | n/a | n/a |
| C90099Ca | CLIA Kit for Canine Matrix Metalloproteinase 13(MMP13) | Dog | n/a | n/a | n/a |
| C90099Po | CLIA Kit for Porcine Matrix Metalloproteinase 13(MMP13) | Pig | n/a | n/a | n/a |
| C90099Bo | CLIA Kit for Bovine Matrix Metalloproteinase 13(MMP13) | Cattle | n/a | n/a | n/a |
| C90099Cp | CLIA Kit for Caprine Matrix Metalloproteinase 13(MMP13) | Goat | n/a | n/a | n/a |
| C90099Eq | CLIA Kit for Equine Matrix Metalloproteinase 13(MMP13) | Horse | n/a | n/a | n/a |
| C90099Ga | CLIA Kit for Gallinaceous Matrix Metalloproteinase 13(MMP13) | Chicken | n/a | n/a | n/a |