Matrix Metalloproteinase 13 (MMP13)
CLG3; Collagenase 3
 HGNC 7159
 MGI 1340026
 OMIM 600108
 RGD 620196
 UCSC uc001phl.1
 UniProt P45452
 USCN 90099
Matrix Metalloproteinase 13 (MMP13)
MMP-13 has been proposed to participate in aggrecan degradation associated with osteoarthritis and cleavage of type II collagen in osteoarthritic cartilage explants and in tumor progression and metastasis . In addition, it can cleave type I, III, IV, IX, X and XIV collagens and fibronectin. MMP-13 is likely to play a crucial role in the modulation of extracellular matrix degradation and cell-matrix interactions .MMP-13 is expressed by several metastatic tumors including breast carcinomas, chondrosarcomas, head and neck carcinomas, and in degenerative bone diseases including rheumatoid arthritis. Wild type and mutant p53, a tumor suppressor gene, differentially regulate MMP-13 gene expression . Members of the activator protein-1 and core-binding factor families increase MMP-13 promoter activity in normal, differentiating osteoblasts .
 ELISA Kits(Enzyme-linked immunosorbent assay Kits)
Catalog Product Name Organism Manual
E90099HuELISA Kit for Matrix Metalloproteinase 13 (MMP13)Homo sapiens (Human)  PDF
E90099MuELISA Kit for Matrix Metalloproteinase 13 (MMP13)Mus musculus (Mouse)  PDF
E90099RaELISA Kit for Matrix Metalloproteinase 13 (MMP13)Rattus norvegicus (Rat)  PDF
E90099RbELISA Kit for Matrix Metalloproteinase 13 (MMP13)Oryctolagus cuniculus (Rabbit)  PDF
E90099CaELISA Kit for Matrix Metalloproteinase 13 (MMP13)Canis familiaris; Canine (Dog)  PDF
E90099PoELISA Kit for Matrix Metalloproteinase 13 (MMP13)Sus scrofa; Porcine (Pig)  PDF
E90099BoELISA Kit for Matrix Metalloproteinase 13 (MMP13)Bos taurus; Bovine (Cattle)  PDF
E90099CpELISA Kit for Matrix Metalloproteinase 13 (MMP13)Capra hircus; Caprine (Goat)  PDF
E90099EqELISA Kit for Matrix Metalloproteinase 13 (MMP13)Equus caballus; Equine (Horse)  PDF
E90099GaELISA Kit for Matrix Metalloproteinase 13 (MMP13)Chicken (Gallus)  PDF
 CLIA Kits(Chemiluminescent immunoassay Kits)
Catalog Product Name Organism Manual
C90099HuCLIA Kit for Matrix Metalloproteinase 13 (MMP13)Homo sapiens (Human)  n/a
C90099MuCLIA Kit for Matrix Metalloproteinase 13 (MMP13)Mus musculus (Mouse)  n/a
C90099RaCLIA Kit for Matrix Metalloproteinase 13 (MMP13)Rattus norvegicus (Rat)  n/a
C90099RbCLIA Kit for Matrix Metalloproteinase 13 (MMP13)Oryctolagus cuniculus (Rabbit)  n/a
C90099CaCLIA Kit for Matrix Metalloproteinase 13 (MMP13)Canis familiaris; Canine (Dog)  n/a
C90099PoCLIA Kit for Matrix Metalloproteinase 13 (MMP13)Sus scrofa; Porcine (Pig)  n/a
C90099BoCLIA Kit for Matrix Metalloproteinase 13 (MMP13)Bos taurus; Bovine (Cattle)  n/a
C90099CpCLIA Kit for Matrix Metalloproteinase 13 (MMP13)Capra hircus; Caprine (Goat)  n/a
C90099EqCLIA Kit for Matrix Metalloproteinase 13 (MMP13)Equus caballus; Equine (Horse)  n/a
C90099GaCLIA Kit for Matrix Metalloproteinase 13 (MMP13)Chicken (Gallus)  n/a