Mammary Serine Protease Inhibitor (Maspin)

SERPINB5; PI5; Protease Inhibitor 5; Serpin Peptidase Inhibitor Clade B Member 5

Maspin is a serpin and tumor suppressor gene.It has been associated with prostate cancer and breast cancer.It has also been associated with tumors of the pancreas.It was identified in 1994.In normal cells expressing SERPINB5, the SERPINB5 promoter is unmethylated and the promoter region has acetylated histones and an accessible chromatin structure. In contrast, normal cells that do not express SERPINB5 have a completely methylated SERPINB5 promoter with hypoacetylated histones, an inaccessible chromatin structure, and a transcriptional repression that is relieved by inhibition of DNA methylation. These findings indicated that cytosine methylation is important in the establishment and maintenance of cell type-restricted gene expression.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD386Hu01 Recombinant Mammary Serine Protease Inhibitor (Maspin) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD386Hu01 Polyclonal Antibody to Mammary Serine Protease Inhibitor (Maspin) WB; IHC; ICC; IP.
MAD386Hu21 Monoclonal Antibody to Mammary Serine Protease Inhibitor (Maspin) WB; IHC; ICC; IP.
Assay Kits SED386Hu ELISA Kit for Mammary Serine Protease Inhibitor (Maspin) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Mammary Serine Protease Inhibitor (Maspin) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Mammary Serine Protease Inhibitor (Maspin) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Mammary Serine Protease Inhibitor (Maspin) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Mammary Serine Protease Inhibitor (Maspin) CLIA Kit Customized Service Offer
n/a ELISA Kit for Mammary Serine Protease Inhibitor (Maspin) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Mammary Serine Protease Inhibitor (Maspin) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Mammary Serine Protease Inhibitor (Maspin) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Mammary Serine Protease Inhibitor (Maspin) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Mammary Serine Protease Inhibitor (Maspin) CLIA Kit Customized Service Offer
n/a ELISA Kit for Mammary Serine Protease Inhibitor (Maspin) ELISA Kit Customized Service Offer