Mammary Serine Protease Inhibitor (Maspin)
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SERPINB5; PI5; Protease Inhibitor 5; Serpin Peptidase Inhibitor Clade B Member 5
 HGNC 8949
 MGI 109579
 PubMed 10655109
 RGD 69342
 UniProt P36952
 USCN D386
 Wiki Maspin
Mammary Serine Protease Inhibitor (Maspin)
Maspin is a serpin and tumor suppressor gene.It has been associated with prostate cancer and breast cancer.It has also been associated with tumors of the pancreas.It was identified in 1994.In normal cells expressing SERPINB5, the SERPINB5 promoter is unmethylated and the promoter region has acetylated histones and an accessible chromatin structure. In contrast, normal cells that do not express SERPINB5 have a completely methylated SERPINB5 promoter with hypoacetylated histones, an inaccessible chromatin structure, and a transcriptional repression that is relieved by inhibition of DNA methylation. These findings indicated that cytosine methylation is important in the establishment and maintenance of cell type-restricted gene expression.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD386Hu01 Recombinant Mammary Serine Protease Inhibitor (Maspin) SDS-PAGE; WB; ELISA; IP.
Antibodies MAD386Hu21 Monoclonal Antibody to Mammary Serine Protease Inhibitor (Maspin) WB, ICC, IHC-P, IHC-F, ELISA
PAD386Hu01 Polyclonal Antibody to Mammary Serine Protease Inhibitor (Maspin) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SED386Hu ELISA Kit for Mammary Serine Protease Inhibitor (Maspin) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a