Major Histocompatibility Complex Class I C (MHCC)
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MHC-C;; HLAC; HLA-JY3; HLC-C; HLA-C; PSORS1 Leukocyte Antigen C; HLA class I histocompatibility antigen, Cw-7 alpha chain
 HGNC 4933
 MGI 95904
 PubMed 18987136
 UniProt P10321
 USCN C086
 Wiki HLA-C
Major Histocompatibility Complex Class I C (MHCC)
HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC086Hu01 Recombinant Major Histocompatibility Complex Class I C (MHCC) SDS-PAGE; WB; ELISA; IP.
Antibodies MAC086Hu22 Monoclonal Antibody to Major Histocompatibility Complex Class I C (MHCC) WB, ICC, IHC-P, IHC-F, ELISA
PAC086Hu01 Polyclonal Antibody to Major Histocompatibility Complex Class I C (MHCC) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits n/a n/a n/a
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a