Major Basic Protein (MBP)
[ Edit ]
PRG2; BMPG; Proteoglycan 2; Bone Marrow,Natural Killer Cell Activator; Eosinophil Granule Major Basic Protein; Proteoglycan 2,Bone Marrow; Pregnancy-associated major basic
 HGNC 9362
 MGI 103294
 PubMed 7230899
 RGD 69336
 UniProt P13727
 USCN B650
 Wiki MBP
Major Basic Protein (MBP)
Major basic protein The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases.PRG2 is a 117-residue protein that predominates in eosinophil granules. It is a potent enzyme against helminths and is toxic towards bacteria and mammalian cells in vitro.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB650Hu01 Recombinant Major Basic Protein (MBP) SDS-PAGE; WB; ELISA; IP.
Antibodies MAB650Hu21 Monoclonal Antibody to Major Basic Protein (MBP) WB, ICC, IHC-P, IHC-F, ELISA
PAB650Hu01 Polyclonal Antibody to Major Basic Protein (MBP) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEB650Hu ELISA Kit for Major Basic Protein (MBP) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB650Mu01 Recombinant Major Basic Protein (MBP) SDS-PAGE; WB; ELISA; IP.
RPB650Mu02 Recombinant Major Basic Protein (MBP) SDS-PAGE; WB; ELISA; IP.
Antibodies PAB650Mu01 Polyclonal Antibody to Major Basic Protein (MBP) WB, ICC, IHC-P, IHC-F, ELISA
PAB650Mu02 Polyclonal Antibody to Major Basic Protein (MBP) WB, ICC, IHC-P, IHC-F, ELISA
PAB650Mu71 Biotin-Linked Antibody to Major Basic Protein (MBP) IHC;WB;ELISA
Assay Kits SEB650Mu ELISA Kit for Major Basic Protein (MBP) Enzyme-linked immunosorbent assay
SCB650Mu CLIA Kit for Major Basic Protein (MBP) Chemiluminescent immunoassay
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB650Ra01 Recombinant Major Basic Protein (MBP) SDS-PAGE; WB; ELISA; IP.
Antibodies PAB650Ra01 Polyclonal Antibody to Major Basic Protein (MBP) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits n/a n/a n/a
Organism species: Sus scrofa; Porcine (Pig)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB650Po01 Recombinant Major Basic Protein (MBP) SDS-PAGE; WB; ELISA; IP.
Antibodies PAB650Po01 Polyclonal Antibody to Major Basic Protein (MBP) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits n/a n/a n/a