Loricrin (LOR)
 HGNC 6663
 MGI 96816
 RGD 1559993
 UniProt P23490
 USCN C568
Loricrin (LOR)
Loricrin is a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in this gene are associated with Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases.
There were multiple sequence variants within these 2 size class alleles due to various deletions of 12 bp (4 amino acids) in the major loop of this glycine loop domain. By use of a specific loricrin antibody in immunogold electron microscopy, they showed that loricrin appears initially in the granular layer of human epidermis and forms composite keratohyalin granules with profilaggrin, but localizes to the cell periphery (cell envelope) of fully differentiated stratum corneum cells.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC568Hu01 Recombinant Loricrin (LOR) SDS-PAGE; WB; ELISA; IP.
Antibodies MAC568Hu22 Monoclonal Antibody to Loricrin (LOR) WB, ICC, IHC-P, IHC-F, ELISA
PAC568Hu01 Polyclonal Antibody to Loricrin (LOR) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEC568Hu ELISA Kit for Loricrin (LOR) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a