Linker For Activation Of T-Cell (LAT)
LAT1; Pp36; Linker Of Activated T Cells
LAT1; Pp36; Linker Of Activated T Cells
-90270.jpg "Linker For Activation Of T-Cell (LAT)")
Linker of Activated T cells also known as LAT is a protein which is encoded by the LAT gene. Alternative splicing results in multiple transcript variants encoding different isoforms.
The protein encoded by this gene is phosphorylated by ZAP70/SYK protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts (also known as glycosphingolipid-enriched microdomains or GEMs) and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement.
ELISA Kits(Enzyme-linked immunosorbent assay Kits)
CLIA Kits(Chemiluminescent immunoassay Kits)
| Catalog | Product Name | Organism | Manual |
|---|---|---|---|
| E90270Hu | ELISA Kit for Linker For Activation Of T-Cell (LAT) | Homo sapiens (Human) | |
| E90270Mu | ELISA Kit for Linker For Activation Of T-Cell (LAT) | Mus musculus (Mouse) | |
| E90270Ra | ELISA Kit for Linker For Activation Of T-Cell (LAT) | Rattus norvegicus (Rat) |
| Catalog | Product Name | Organism | Manual |
|---|---|---|---|
| C90270Hu | CLIA Kit for Linker For Activation Of T-Cell (LAT) | Homo sapiens (Human) | n/a |
| C90270Mu | CLIA Kit for Linker For Activation Of T-Cell (LAT) | Mus musculus (Mouse) | n/a |
| C90270Ra | CLIA Kit for Linker For Activation Of T-Cell (LAT) | Rattus norvegicus (Rat) | n/a |