Like Glycosyltransferase (LARGE)
Glycosyltransferase-like protein LARGE1; Acetylglucosaminyltransferase-like 1A
LARGE, which is one of the largest in the human genome, encodes a member of the N-acetylglucosaminyltransferase gene family. It encodes a glycosyltransferase which participates in glycosylation of alpha-dystroglycan, and may carry out the synthesis of glycoprotein and glycosphingolipid sugar chains.
It may also be involved in the addition of a repeated disaccharide unit. Mutations in this gene cause MDC1D, a novel form of congenital muscular dystrophy with severe mental retardation and abnormal glycosylation of alpha-dystroglycan. Alternative splicing of this gene results in two transcript variants that encode the same protein.LARGE protein contains an N-terminal transmembrane domain, a coiled-coil domain, and 2 catalytic domains.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPH936Hu01 | Recombinant Like Glycosyltransferase (LARGE) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAH936Hu01 | Polyclonal Antibody to Like Glycosyltransferase (LARGE) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for Like Glycosyltransferase (LARGE) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Like Glycosyltransferase (LARGE) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Like Glycosyltransferase (LARGE) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Like Glycosyltransferase (LARGE) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Like Glycosyltransferase (LARGE) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Like Glycosyltransferase (LARGE) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Like Glycosyltransferase (LARGE) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Like Glycosyltransferase (LARGE) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Like Glycosyltransferase (LARGE) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Like Glycosyltransferase (LARGE) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Like Glycosyltransferase (LARGE) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Like Glycosyltransferase (LARGE) | ELISA Kit Customized Service Offer |