Klotho (KL)
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 HGNC 6344
 MGI 1101771
 PubMed 9464267
 RGD 620396
 UniProt Q9UEF7
 USCN H757
 Wiki KL
Klotho (KL)
Klotho is a type-I membrane protein that is related to β-glucuronidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss.
Klotho is a transmembrane protein that, in addition to other effects, provides some control over the sensitivity of the organism to insulin and appears to be involved in aging. Its discovery was documented in 1997 by Kuro-o et al. The name of the gene comes from Klotho or Clotho, one of the Moirae, or Fates, in Greek mythology.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH757Hu01 Recombinant Klotho (KL) SDS-PAGE; WB; ELISA; IP.
Antibodies MAH757Hu21 Monoclonal Antibody to Klotho (KL) WB, ICC, IHC-P, IHC-F, ELISA
PAH757Hu01 Polyclonal Antibody to Klotho (KL) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEH757Hu ELISA Kit for Klotho (KL) Enzyme-linked immunosorbent assay
SCH757Hu CLIA Kit for Klotho (KL) Chemiluminescent immunoassay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH757Mu01 Recombinant Klotho (KL) SDS-PAGE; WB; ELISA; IP.
RPH757Mu02 Recombinant Klotho (KL) SDS-PAGE; WB; ELISA; IP.
Antibodies PAH757Mu01 Polyclonal Antibody to Klotho (KL) WB, ICC, IHC-P, IHC-F, ELISA
PAH757Mu02 Polyclonal Antibody to Klotho (KL) WB, ICC, IHC-P, IHC-F, ELISA
PAH757Mu71 Biotin-Linked Antibody to Klotho (KL) IHC;WB;ELISA
PAH757Mu81 FITC-Linked Antibody to Klotho (KL) IHC;ICC;IF;WB
Assay Kits SEH757Mu ELISA Kit for Klotho (KL) Enzyme-linked immunosorbent assay
SCH757Mu CLIA Kit for Klotho (KL) Chemiluminescent immunoassay
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH757Ra01 Recombinant Klotho (KL) SDS-PAGE; WB; ELISA; IP.
Antibodies MAH757Ra21 Monoclonal Antibody to Klotho (KL) WB, ICC, IHC-P, IHC-F, ELISA
PAH757Ra01 Polyclonal Antibody to Klotho (KL) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEH757Ra ELISA Kit for Klotho (KL) Enzyme-linked immunosorbent assay