Inversin (INVS)
NPH2; INV; NPHP2; Nephronophthisis 2,Infantile
 HGNC 17870
 MGI 1335082
 OMIM 243305
 RGD 1563359
 UCSC uc004bap.1
 UniProt Q9Y283
 USCN 92545
Inversin (INVS)
Inversin, also known as INVS is a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Two transcript variants encoding distinct isoforms have been identified for this gene.
Required for normal renal development and establishment of left-right axis. Widely expressed. Strongly expressed in the primary cilia of renal tubular cells.
 ELISA Kits(Enzyme-linked immunosorbent assay Kits)
Catalog Product Name Organism Manual
E92545HuELISA Kit for Inversin (INVS)Homo sapiens (Human)  n/a
E92545MuELISA Kit for Inversin (INVS)Mus musculus (Mouse)  n/a
E92545RaELISA Kit for Inversin (INVS)Rattus norvegicus (Rat)  n/a
 CLIA Kits(Chemiluminescent immunoassay Kits)
Catalog Product Name Organism Manual
C92545HuCLIA Kit for Inversin (INVS)Homo sapiens (Human)  n/a
C92545MuCLIA Kit for Inversin (INVS)Mus musculus (Mouse)  n/a
C92545RaCLIA Kit for Inversin (INVS)Rattus norvegicus (Rat)  n/a