Cubilin (CUBN)
IFCR; MGA1; gp280; Intrinsic Factor Cobalamin Receptor; 460 kDa receptor; Intestinal intrinsic factor receptor; Intrinsic factor-vitamin B12 receptor
Cubilin (CUBN) acts as a receptor for intrinsic factor-vitamin B12 complexes. The role of receptor is supported by the presence of 27 CUB domains. Cubulin is located within the epithelium of intestine and kidney. Mutations in CUBN may play a role in autosomal recessive megaloblastic anemia.
Cotransporter which plays a role in lipoprotein, vitamin and iron metabolism, by facilitating their uptake. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the GIF-cobalamin complex. The binding of all ligands required calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal tubules and embryonic yolk sac.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPC411Hu01 | Recombinant Cubilin (CUBN) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPC411Hu02 | Recombinant Cubilin (CUBN) | Positive Control; Immunogen; SDS-PAGE; WB. | |
APC411Hu02 | Active Cubilin (CUBN) | Cell culture; Activity Assays. | |
Antibodies | PAC411Hu01 | Polyclonal Antibody to Cubilin (CUBN) | WB; IHC; ICC; IP. |
MAC411Hu22 | Monoclonal Antibody to Cubilin (CUBN) | WB; IHC; ICC; IP. | |
PAC411Hu02 | Polyclonal Antibody to Cubilin (CUBN) | WB; IHC; ICC; IP. | |
Assay Kits | SEC411Hu | ELISA Kit for Cubilin (CUBN) | Enzyme-linked immunosorbent assay for Antigen Detection. |
AEC411Hu | ELISA Kit for Anti-Cubilin Antibody (Anti-CUBN) | Enzyme-linked immunosorbent assay for Antibody Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPC411Mu01 | Recombinant Cubilin (CUBN) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPC411Mu02 | Recombinant Cubilin (CUBN) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAC411Mu01 | Polyclonal Antibody to Cubilin (CUBN) | WB; IHC; ICC; IP. |
PAC411Mu02 | Polyclonal Antibody to Cubilin (CUBN) | WB; IHC; ICC; IP. | |
LAC411Mu71 | Biotin-Linked Polyclonal Antibody to Cubilin (CUBN) | WB; IHC; ICC. | |
LAC411Mu81 | FITC-Linked Polyclonal Antibody to Cubilin (CUBN) | WB; IHC; ICC; IF. | |
Assay Kits | SEC411Mu | ELISA Kit for Cubilin (CUBN) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPC411Ra01 | Recombinant Cubilin (CUBN) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPC411Ra02 | Recombinant Cubilin (CUBN) | Positive Control; Immunogen; SDS-PAGE; WB. | |
RPC411Ra03 | Recombinant Cubilin (CUBN) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAC411Ra01 | Polyclonal Antibody to Cubilin (CUBN) | WB; IHC; ICC; IP. |
PAC411Ra02 | Polyclonal Antibody to Cubilin (CUBN) | WB; IHC; ICC; IP. | |
PAC411Ra03 | Polyclonal Antibody to Cubilin (CUBN) | WB; IHC; ICC; IP. | |
LAC411Ra71 | Biotin-Linked Polyclonal Antibody to Cubilin (CUBN) | WB; IHC; ICC. | |
Assay Kits | SEC411Ra | ELISA Kit for Cubilin (CUBN) | Enzyme-linked immunosorbent assay for Antigen Detection. |