Integral Membrane Protein 2B (ITM2B)
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ABRI; BRI; BRI2; BRICD2B; E25B; E3-16; FBD
 HGNC 6174
 MGI 1309517
 PubMed 17965014
 RGD 620727
 UniProt Q9Y287
 USCN L634
 Wiki ITM2B
Integral Membrane Protein 2B (ITM2B)
ITM2B or BRI2 is a gene located on chromosom 13. The gene is connected to Familial Danish Disease (FDD) and Familial British Disease (FBD) causing amyloid and pre-filbrillar effects similar to those seen in Alzheimers Disease (AD).
The BRI cDNA encodes a predicted protein of 266 amino acids. The first ATG is located 150 basepairs downstream of an in-frame TAG stop codon and has a classic Kozak consensus sequence. Hydropathy analysis indicated the presence of a putative single transmembrane-spanning domain between amino acids 52 and 74, indicating that this highly insoluble molecule is a type II integral transmembrane protein with the C-terminal part being extracellular. A potential N-glycosylation site was identified at asparagine-170.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a