Insulin Like Growth Factor Binding Protein 3 (IGFBP3)
BP53; IBP3; Growth Hormone-Dependent Binding Protein; Acid Stable Subunit Of The 140 K IGF Complex
BP53; IBP3; Growth Hormone-Dependent Binding Protein; Acid Stable Subunit Of The 140 K IGF Complex
-90054.jpg "Insulin Like Growth Factor Binding Protein 3 (IGFBP3)")
The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors.
IGFBP3 protein levels decrease during the progression of prostate cancer from benign prostatic hyperplasia (BPH) to its metastatic form.Although, production of the protein does not cease completely. IGFBP3 is still made (at a lower level) by prostate cancer cells and secreted into the surrounding environment. However, instead of the full length, functional protein, IGFBP3 is found to be cleaved.
ELISA Kits(Enzyme-linked immunosorbent assay Kits)
CLIA Kits(Chemiluminescent immunoassay Kits)
| Catalog | Product Name | Organism | Manual |
|---|---|---|---|
| E90054Hu | ELISA Kit for Insulin Like Growth Factor Binding Protein 3 (IGFBP3) | Homo sapiens (Human) | |
| E90054Mu | ELISA Kit for Insulin Like Growth Factor Binding Protein 3 (IGFBP3) | Mus musculus (Mouse) | |
| E90054Ra | ELISA Kit for Insulin Like Growth Factor Binding Protein 3 (IGFBP3) | Rattus norvegicus (Rat) | |
| E90054Po | ELISA Kit for Insulin Like Growth Factor Binding Protein 3 (IGFBP3) | Sus scrofa; Porcine (Pig) | |
| E90054Bo | ELISA Kit for Insulin Like Growth Factor Binding Protein 3 (IGFBP3) | Bos taurus; Bovine (Cattle) | |
| E90054Cp | ELISA Kit for Insulin Like Growth Factor Binding Protein 3 (IGFBP3) | Capra hircus; Caprine (Goat) | |
| E90054Eq | ELISA Kit for Insulin Like Growth Factor Binding Protein 3 (IGFBP3) | Equus caballus; Equine (Horse) | |
| E90054Ga | ELISA Kit for Insulin Like Growth Factor Binding Protein 3 (IGFBP3) | Chicken (Gallus) | |
| E90054Fi | ELISA Kit for Insulin Like Growth Factor Binding Protein 3 (IGFBP3) | Danio rerio (Zebrafish) |
| Catalog | Product Name | Organism | Manual |
|---|---|---|---|
| C90054Hu | CLIA Kit for Insulin Like Growth Factor Binding Protein 3 (IGFBP3) | Homo sapiens (Human) | n/a |
| C90054Mu | CLIA Kit for Insulin Like Growth Factor Binding Protein 3 (IGFBP3) | Mus musculus (Mouse) | n/a |
| C90054Ra | CLIA Kit for Insulin Like Growth Factor Binding Protein 3 (IGFBP3) | Rattus norvegicus (Rat) | n/a |
| C90054Po | CLIA Kit for Insulin Like Growth Factor Binding Protein 3 (IGFBP3) | Sus scrofa; Porcine (Pig) | n/a |
| C90054Bo | CLIA Kit for Insulin Like Growth Factor Binding Protein 3 (IGFBP3) | Bos taurus; Bovine (Cattle) | n/a |
| C90054Cp | CLIA Kit for Insulin Like Growth Factor Binding Protein 3 (IGFBP3) | Capra hircus; Caprine (Goat) | n/a |
| C90054Eq | CLIA Kit for Insulin Like Growth Factor Binding Protein 3 (IGFBP3) | Equus caballus; Equine (Horse) | n/a |
| C90054Ga | CLIA Kit for Insulin Like Growth Factor Binding Protein 3 (IGFBP3) | Chicken (Gallus) | n/a |
| C90054Fi | CLIA Kit for Insulin Like Growth Factor Binding Protein 3 (IGFBP3) | Danio rerio (Zebrafish) | n/a |