Inducible T-Cell Co Stimulator Ligand (ICOSLG)
CD275; B7-H2; B7H2; B7RP-1; B7RP1; GL50; ICOS-L; ICOSL; LICOS
 HGNC 17087
 MGI 1354701
 PubMed 21958057
 RGD 1562791
 UniProt O75144
 USCN A787
 Wiki ICOSLG
Inducible T-Cell Co Stimulator Ligand (ICOSLG)
ICOSLG has also been designated as CD275 (cluster of differentiation 275).BIAcore analysis by Yoshinaga et al. (2000) indicated that B7RP1 binds preferentially to ICOS and does not bind to CTLA4. Flow cytometric analysis demonstrated that tumor necrosis factor-alpha  enhances B7RP1 expression on B cells and monocytes, but decreases its expression on dendritic cells.
B7RP1 fusion protein or cells expressing B7RP1 enhanced T-cell proliferation and interleukin-2 (IL2; 147680)-dependent cytokine production (gamma-interferon and IL10 but not IL2) in response to anti-CD3 stimulation. This enhancement could be blocked by soluble ICOS.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA787Hu01 Recombinant Inducible T-Cell Co Stimulator Ligand (ICOSLG) SDS-PAGE; WB; ELISA; IP.
Antibodies MAA787Hu21 Monoclonal Antibody to Inducible T-Cell Co Stimulator Ligand (ICOSLG) WB, ICC, IHC-P, IHC-F, ELISA
PAA787Hu01 Polyclonal Antibody to Inducible T-Cell Co Stimulator Ligand (ICOSLG) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEA787Hu ELISA Kit for Inducible T-Cell Co Stimulator Ligand (ICOSLG) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a