Inducible T-Cell Co Stimulator Ligand (ICOSLG)

CD275; B7-H2; B7H2; B7RP-1; B7RP1; GL50; ICOS-L; ICOSL; LICOS; B7-like protein Gl50; B7-related protein 1

ICOSLG has also been designated as CD275 (cluster of differentiation 275).BIAcore analysis by Yoshinaga et al. (2000) indicated that B7RP1 binds preferentially to ICOS and does not bind to CTLA4. Flow cytometric analysis demonstrated that tumor necrosis factor-alpha  enhances B7RP1 expression on B cells and monocytes, but decreases its expression on dendritic cells.

B7RP1 fusion protein or cells expressing B7RP1 enhanced T-cell proliferation and interleukin-2 (IL2; 147680)-dependent cytokine production (gamma-interferon and IL10 but not IL2) in response to anti-CD3 stimulation. This enhancement could be blocked by soluble ICOS.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA787Hu01 Recombinant Inducible T-Cell Co Stimulator Ligand (ICOSLG) Positive Control; Immunogen; SDS-PAGE; WB.
EPA787Hu61 Eukaryotic Inducible T-Cell Co Stimulator Ligand (ICOSLG) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA787Hu01 Polyclonal Antibody to Inducible T-Cell Co Stimulator Ligand (ICOSLG) WB; IHC; ICC; IP.
MAA787Hu21 Monoclonal Antibody to Inducible T-Cell Co Stimulator Ligand (ICOSLG) WB; IHC; ICC; IP.
MAA787Hu22 Monoclonal Antibody to Inducible T-Cell Co Stimulator Ligand (ICOSLG) WB; IHC; ICC; IP.
Assay Kits SEA787Hu ELISA Kit for Inducible T-Cell Co Stimulator Ligand (ICOSLG) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA787Mu01 Recombinant Inducible T-Cell Co Stimulator Ligand (ICOSLG) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA787Mu01 Polyclonal Antibody to Inducible T-Cell Co Stimulator Ligand (ICOSLG) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Inducible T-Cell Co Stimulator Ligand (ICOSLG) CLIA Kit Customized Service Offer
n/a ELISA Kit for Inducible T-Cell Co Stimulator Ligand (ICOSLG) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Inducible T-Cell Co Stimulator Ligand (ICOSLG) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Inducible T-Cell Co Stimulator Ligand (ICOSLG) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Inducible T-Cell Co Stimulator Ligand (ICOSLG) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Inducible T-Cell Co Stimulator Ligand (ICOSLG) CLIA Kit Customized Service Offer
n/a ELISA Kit for Inducible T-Cell Co Stimulator Ligand (ICOSLG) ELISA Kit Customized Service Offer