Inducible T-Cell Co Stimulator Ligand (ICOSLG)
CD275; B7-H2; B7H2; B7RP-1; B7RP1; GL50; ICOS-L; ICOSL; LICOS; B7-like protein Gl50; B7-related protein 1
ICOSLG has also been designated as CD275 (cluster of differentiation 275).BIAcore analysis by Yoshinaga et al. (2000) indicated that B7RP1 binds preferentially to ICOS and does not bind to CTLA4. Flow cytometric analysis demonstrated that tumor necrosis factor-alpha enhances B7RP1 expression on B cells and monocytes, but decreases its expression on dendritic cells.
B7RP1 fusion protein or cells expressing B7RP1 enhanced T-cell proliferation and interleukin-2 (IL2; 147680)-dependent cytokine production (gamma-interferon and IL10 but not IL2) in response to anti-CD3 stimulation. This enhancement could be blocked by soluble ICOS.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA787Hu01 | Recombinant Inducible T-Cell Co Stimulator Ligand (ICOSLG) | Positive Control; Immunogen; SDS-PAGE; WB. |
| EPA787Hu61 | Eukaryotic Inducible T-Cell Co Stimulator Ligand (ICOSLG) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAA787Hu01 | Polyclonal Antibody to Inducible T-Cell Co Stimulator Ligand (ICOSLG) | WB; IHC; ICC; IP. |
| MAA787Hu21 | Monoclonal Antibody to Inducible T-Cell Co Stimulator Ligand (ICOSLG) | WB; IHC; ICC; IP. | |
| MAA787Hu22 | Monoclonal Antibody to Inducible T-Cell Co Stimulator Ligand (ICOSLG) | WB; IHC; ICC; IP. | |
| Assay Kits | SEA787Hu | ELISA Kit for Inducible T-Cell Co Stimulator Ligand (ICOSLG) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPA787Mu01 | Recombinant Inducible T-Cell Co Stimulator Ligand (ICOSLG) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAA787Mu01 | Polyclonal Antibody to Inducible T-Cell Co Stimulator Ligand (ICOSLG) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for Inducible T-Cell Co Stimulator Ligand (ICOSLG) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Inducible T-Cell Co Stimulator Ligand (ICOSLG) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Inducible T-Cell Co Stimulator Ligand (ICOSLG) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Inducible T-Cell Co Stimulator Ligand (ICOSLG) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Inducible T-Cell Co Stimulator Ligand (ICOSLG) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Inducible T-Cell Co Stimulator Ligand (ICOSLG) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Inducible T-Cell Co Stimulator Ligand (ICOSLG) | ELISA Kit Customized Service Offer |