Indoleamine-2,3-Dioxygenase (IDO)
CD107B; INDO; Indoleamine-Pyrrole 2,3 Dioxygenase
 HGNC 6059
 MGI 96416
 PubMed 20693847
 RGD 619989
 UniProt P14902
 USCN B547
 Wiki IDO
Indoleamine-2,3-Dioxygenase (IDO)
Indoleamine 2,3-dioxygenase (IDO) is an IFN-γ inducible 42 kDa enzyme that catalyzes the degradation of the essential amino acid L-tryptophan to N-formylkynurenine. The gene encoding human IDO maps to chromosome 8p12-p11.
IDO, also known as INDO, is an important modulator of immunological responses and protects allogeneic concepti from alloreactive maternal lymphocytes. IDO mediates an interesting inhibitory effect of HeLa cells co-cultured with human PBLs. The ILN-2-induced proliferation response of PBLs is diminished in the presence of HeLa cells while an IDO inhbitor negates this effect. Flow cytometric analysis indicates both mature and immautre CD123-positive dentritic cells suppress T cell activity using IDO.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB547Hu01 Recombinant Indoleamine-2,3-Dioxygenase (IDO) SDS-PAGE; WB; ELISA; IP.
Antibodies MAB547Hu22 Monoclonal Antibody to Indoleamine-2,3-Dioxygenase (IDO) WB, ICC, IHC-P, IHC-F, ELISA
PAB547Hu01 Polyclonal Antibody to Indoleamine-2,3-Dioxygenase (IDO) WB, ICC, IHC-P, IHC-F, ELISA
PAB547Hu71 Biotin-Linked Antibody to Indoleamine-2,3-Dioxygenase (IDO) IHC;WB;ELISA
PAB547Hu81 FITC-Linked Antibody to Indoleamine-2,3-Dioxygenase (IDO) IHC;ICC;IF;WB
Assay Kits SEB547Hu ELISA Kit for Indoleamine-2,3-Dioxygenase (IDO) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB547Mu01 Recombinant Indoleamine-2,3-Dioxygenase (IDO) SDS-PAGE; WB; ELISA; IP.
RPB547Mu02 Recombinant Indoleamine-2,3-Dioxygenase (IDO) SDS-PAGE; WB; ELISA; IP.
Antibodies PAB547Mu01 Polyclonal Antibody to Indoleamine-2,3-Dioxygenase (IDO) WB, ICC, IHC-P, IHC-F, ELISA
PAB547Mu02 Polyclonal Antibody to Indoleamine-2,3-Dioxygenase (IDO) IWB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEB547Mu ELISA Kit for Indoleamine-2,3-Dioxygenase (IDO) Enzyme-linked immunosorbent assay
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB547Ra01 Recombinant Indoleamine-2,3-Dioxygenase (IDO) SDS-PAGE; WB; ELISA; IP.
RPB547Ra02 Recombinant Indoleamine-2,3-Dioxygenase (IDO) SDS-PAGE; WB; ELISA; IP.
Antibodies MAB547Ra21 Monoclonal Antibody to Indoleamine-2,3-Dioxygenase (IDO) WB, ICC, IHC-P, IHC-F, ELISA
PAB547Ra01 Polyclonal Antibody to Indoleamine-2,3-Dioxygenase (IDO) WB, ICC, IHC-P, IHC-F, ELISA
PAB547Ra02 Polyclonal Antibody to Indoleamine-2,3-Dioxygenase (IDO) WB, ICC, IHC-P, IHC-F, ELISA
PAB547Ra71 Biotin-Linked Antibody to Indoleamine-2,3-Dioxygenase (IDO) IHC;WB;ELISA
Assay Kits SEB547Ra ELISA Kit for Indoleamine-2,3-Dioxygenase (IDO) Enzyme-linked immunosorbent assay