Hypoxia Inducible Factor 1 Alpha (HIF1a)
HIF1-A; MOP1; PASD8; Basic Helix-Loop-Helix Transcription Factor
HIF1-A; MOP1; PASD8; Basic Helix-Loop-Helix Transcription Factor
-90798.jpg "Hypoxia Inducible Factor 1 Alpha (HIF1a)")
The HIF (hypoxia-inducible factor) transcription factor is a member of the basic-helix-loop-helix (bHLH) family of transcription factors and plays an important role in maintaining cellular oxygen homeostasis. The hypoxia-inducible transcription factor 1α (HIF-1α) is the regulated member of the transcription factor heterodimer HIF-1. HIF-1α has emerged as an important drug target in breast and prostate cancer, cardiovascular disease, and ischemia.
HIF-1alpha abundance (and its subsequent activity) is regulated transcriptionally in an NF-κB dependent manner. In addition, the coordinated activity of the prolyl hydroxylases (PHDs) maintain the appropriate balance of HIF-1α protein in the post-translation phase.
ELISA Kits(Enzyme-linked immunosorbent assay Kits)
CLIA Kits(Chemiluminescent immunoassay Kits)
| Catalog | Product Name | Organism | Manual |
|---|---|---|---|
| E90798Hu | ELISA Kit for Hypoxia Inducible Factor 1 Alpha (HIF1a) | Homo sapiens (Human) | |
| E90798Mu | ELISA Kit for Hypoxia Inducible Factor 1 Alpha (HIF1a) | Mus musculus (Mouse) | |
| E90798Ra | ELISA Kit for Hypoxia Inducible Factor 1 Alpha (HIF1a) | Rattus norvegicus (Rat) | |
| E90798Po | ELISA Kit for Hypoxia Inducible Factor 1 Alpha (HIF1a) | Sus scrofa; Porcine (Pig) | |
| E90798Bo | ELISA Kit for Hypoxia Inducible Factor 1 Alpha (HIF1a) | Bos taurus; Bovine (Cattle) | n/a |
| E90798Ov | ELISA Kit for Hypoxia Inducible Factor 1 Alpha (HIF1a) | Ovis aries; Ovine (Sheep) | n/a |
| Catalog | Product Name | Organism | Manual |
|---|---|---|---|
| C90798Hu | CLIA Kit for Hypoxia Inducible Factor 1 Alpha (HIF1a) | Homo sapiens (Human) | n/a |
| C90798Mu | CLIA Kit for Hypoxia Inducible Factor 1 Alpha (HIF1a) | Mus musculus (Mouse) | n/a |
| C90798Ra | CLIA Kit for Hypoxia Inducible Factor 1 Alpha (HIF1a) | Rattus norvegicus (Rat) | n/a |
| C90798Po | CLIA Kit for Hypoxia Inducible Factor 1 Alpha (HIF1a) | Sus scrofa; Porcine (Pig) | n/a |
| C90798Bo | CLIA Kit for Hypoxia Inducible Factor 1 Alpha (HIF1a) | Bos taurus; Bovine (Cattle) | n/a |
| C90798Ov | CLIA Kit for Hypoxia Inducible Factor 1 Alpha (HIF1a) | Ovis aries; Ovine (Sheep) | n/a |