Hepatic Leukemia Factor (HLF)
 HGNC 4977
 MGI 96108
 PubMed 8065331
 UniProt Q16534
 USCN C528
 Wiki HLF
Hepatic Leukemia Factor (HLF)
Hepatic leukemia factor is a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors. The encoded protein forms homodimers or heterodimers with other PAR family members and binds sequence-specific promoter elements to activate transcription. Chromosomal translocations fusing portions of this gene with the E2A gene cause a subset of childhood B-lineage acute lymphoid leukemias. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
The predicted HLF protein contains 295 amino acids and has a calculated molecular mass of 33.3 kD. In vitro transcription and translation yielded a protein of about 43 kD.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a