Heparanase 2 (HPA2)

HPSE2; HPR2; Inactive heparanase-2

Heparanase-2 is a endoglycosidase that degrades heparin sulfate proteoglycans located on the extracellular matrix and cell surface. This protein may be involved in biological processes involving remodeling of the extracellular matrix including angiogenesis and tumor progression. Alternate splicing results in multiple transcript variants.
Endoglycosidase which is a cell surface and extracellular matrix-degrading enzyme. Cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Also implicated in the extravasation of leukocytes and tumor cell lines. Due to its contribution to metastasis and angiogenesis, it is considered to be a potential target for anti-cancer therapies.Widely expressed, with the highest expression in brain, mammary gland, prostate, small intestine, testis and uterus.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Heparanase 2 (HPA2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Heparanase 2 (HPA2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Heparanase 2 (HPA2) Polyclonal Antibody Customized Service Offer
Assay Kits SED395Hu ELISA Kit for Heparanase 2 (HPA2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Heparanase 2 (HPA2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Heparanase 2 (HPA2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Heparanase 2 (HPA2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Heparanase 2 (HPA2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Heparanase 2 (HPA2) ELISA Kit Customized Service Offer