Glyoxylate Reductase/Hydroxypyruvate Reductase (GRHPR)
[ Edit ]
PH2; GLXR; Primary Hyperoxaluria Type 2
 HGNC 4570
 MGI 1923488
 PubMed 14635115
 RGD 1308851
 UniProt Q9UBQ7
 USCN G360
 Wiki GRHPR
Glyoxylate Reductase/Hydroxypyruvate Reductase (GRHPR)
GRHPR encodes an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene.
The GRHPR gene encodes a predicted 328-amino acid protein with a calculated molecular mass of 35.5 kD. By transient transfection of the cDNA clone into COS cells, Cramer et al. (1999) verified that GRHPR encodes an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. Database analysis of human ESTs revealed widespread tissue expression, indicating that the enzyme may have a role in metabolism.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a