Glucose Transporter 4 (GLUT4)
SLC2A4; Solute Carrier Family 2 Member 4(Facilitated Glucose Transporter)
 HGNC 11009
 MGI 95758
 RGD 2711
 UniProt P14672
 USCN C023
Glucose Transporter 4 (GLUT4)
GLUT4 is the insulin-regulated glucose transporter found in adipose tissues and striated muscle (skeletal and cardiac) that is responsible for insulin-regulated glucose disposal.In the absence of insulin, GLUT4 is sequestered in the interior of muscle and fat cells within lipid bilayers of vesicles. Insulin induces the translocation of GLUT4 from intracellular storage sites to the plasma membrane. Insulin binds to the insulin receptor in its dimeric form.
The receptor phosphorylates and subsequently activates IRS-1, which converts PIP2 to PIP3. PIP3 is bound to PKB (protein kinase B), signaling for PDK1 to phosphorylate PKB. Once phosphorylated, PKB is in its active form and phosphorylates other targets that stimulate GLUT4 to be expressed on the plasma membrane.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC023Hu01 Recombinant Glucose Transporter 4 (GLUT4) SDS-PAGE; WB; ELISA; IP.
Antibodies MAC023Hu22 Monoclonal Antibody to Glucose Transporter 4 (GLUT4) WB, ICC, IHC-P, IHC-F, ELISA
PAC023Hu01 Polyclonal Antibody to Glucose Transporter 4 (GLUT4) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEC023Hu ELISA Kit for Glucose Transporter 4 (GLUT4) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC023Mu01 Recombinant Glucose Transporter 4 (GLUT4) SDS-PAGE; WB; ELISA; IP.
RPC023Mu02 Recombinant Glucose Transporter 4 (GLUT4) SDS-PAGE; WB; ELISA; IP.
Antibodies PAC023Mu01 Polyclonal Antibody to Glucose Transporter 4 (GLUT4) WB, ICC, IHC-P, IHC-F, ELISA
PAC023Mu02 Polyclonal Antibody to Glucose Transporter 4 (GLUT4) IWB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEC023Mu ELISA Kit for Glucose Transporter 4 (GLUT4) Enzyme-linked immunosorbent assay
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC023Ra01 Recombinant Glucose Transporter 4 (GLUT4) SDS-PAGE; WB; ELISA; IP.
Antibodies MAC023Ra21 Monoclonal Antibody to Glucose Transporter 4 (GLUT4) WB, ICC, IHC-P, IHC-F, ELISA
PAC023Ra01 Polyclonal Antibody to Glucose Transporter 4 (GLUT4) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEC023Ra ELISA Kit for Glucose Transporter 4 (GLUT4) Enzyme-linked immunosorbent assay
Organism species: Canis familiaris; Canine (Dog)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC023Ca01 Recombinant Glucose Transporter 4 (GLUT4) SDS-PAGE; WB; ELISA; IP.
Antibodies MAC023Ca21 Monoclonal Antibody to Glucose Transporter 4 (GLUT4) WB, ICC, IHC-P, IHC-F, ELISA
PAC023Ca01 Polyclonal Antibody to Glucose Transporter 4 (GLUT4) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEC023Ca ELISA Kit for Glucose Transporter 4 (GLUT4) Enzyme-linked immunosorbent assay