Glucokinase (GCK)
GK; GLK; HHF3; HK4; HKIV; HXKP; MODY2; Hexokinase-D; Hexokinase 4; Maturity Onset Diabetes Of The Young 2
Glucokinase (GK) is a hexokinase isozyme, related homologously and by evolution to at least three other hexokinases. All of the hexokinases can mediate phosphorylation of glucose to glucose-6-phosphate (G6P), which is the first step of both glycogen synthesis and glycolysis. However, glucokinase is coded by a separate gene and its distinctive kinetic properties allow it to serve a different set of functions. Glucokinase has a lower affinity for glucose than the other hexokinases do, and its activity is localized to a few cell types, leaving the other three hexokinases as more important preparers of glucose for glycolysis and glycogen synthesis for most tissues and organs. Because of this reduced affinity, the activity of glucokinase, under usual physiological conditions, varies substantially according to the concentration of glucose.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA667Hu01 | Recombinant Glucokinase (GCK) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA667Hu01 | Polyclonal Antibody to Glucokinase (GCK) | WB; IHC; ICC; IP. |
MAA667Hu22 | Monoclonal Antibody to Glucokinase (GCK) | WB; IHC; ICC; IP. | |
LAA667Hu71 | Biotin-Linked Polyclonal Antibody to Glucokinase (GCK) | WB; IHC; ICC. | |
Assay Kits | SEA667Hu | ELISA Kit for Glucokinase (GCK) | Enzyme-linked immunosorbent assay for Antigen Detection. |
SCA667Hu | CLIA Kit for Glucokinase (GCK) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA667Mu01 | Recombinant Glucokinase (GCK) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPA667Mu02 | Recombinant Glucokinase (GCK) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAA667Mu01 | Polyclonal Antibody to Glucokinase (GCK) | WB; IHC; ICC; IP. |
PAA667Mu02 | Polyclonal Antibody to Glucokinase (GCK) | WB; IHC; ICC; IP. | |
Assay Kits | SEA667Mu | ELISA Kit for Glucokinase (GCK) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA667Ra01 | Recombinant Glucokinase (GCK) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA667Ra01 | Polyclonal Antibody to Glucokinase (GCK) | WB; IHC; ICC; IP. |
MAA667Ra21 | Monoclonal Antibody to Glucokinase (GCK) | WB; IHC; ICC; IP. | |
Assay Kits | SEA667Ra | ELISA Kit for Glucokinase (GCK) | Enzyme-linked immunosorbent assay for Antigen Detection. |