General Transcription Factor IIH, Polypeptide 5 (GTF2H5)
TTD; TFB5; TGF2H5; TTD-A; TTDA; C6orf175; DNA Repair Syndrome Trichothiodystrophy Group A; TFIIH basal transcription factor complex TTD-A subunit
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General Transcription Factor IIH,Polypeptide 5 is a subunit of transcription/repair factor TFIIH, which functions in gene transcription and DNA repair. This protein stimulates ERCC3/XPB ATPase activity to trigger DNA opening during DNA repair, and is implicated in regulating cellular levels of TFIIH. Mutations in this gene result in trichothiodystrophy, complementation group A.
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This protein, called TFB5, is a core component of yeast general transcription and DNA repair factor IIH (TFIIH). Database screening identified a human homolog of 71 amino acids that shares 28% identity with the yeast protein. Giglia-Mari et al. (2004) cloned the human cDNA corresponding to the TFB5 gene from primary fibroblasts.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPD900Hu01 | Recombinant General Transcription Factor IIH, Polypeptide 5 (GTF2H5) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAD900Hu01 | Polyclonal Antibody to General Transcription Factor IIH, Polypeptide 5 (GTF2H5) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for General Transcription Factor IIH, Polypeptide 5 (GTF2H5) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for General Transcription Factor IIH, Polypeptide 5 (GTF2H5) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant General Transcription Factor IIH, Polypeptide 5 (GTF2H5) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to General Transcription Factor IIH, Polypeptide 5 (GTF2H5) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to General Transcription Factor IIH, Polypeptide 5 (GTF2H5) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for General Transcription Factor IIH, Polypeptide 5 (GTF2H5) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for General Transcription Factor IIH, Polypeptide 5 (GTF2H5) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant General Transcription Factor IIH, Polypeptide 5 (GTF2H5) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to General Transcription Factor IIH, Polypeptide 5 (GTF2H5) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to General Transcription Factor IIH, Polypeptide 5 (GTF2H5) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for General Transcription Factor IIH, Polypeptide 5 (GTF2H5) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for General Transcription Factor IIH, Polypeptide 5 (GTF2H5) | ELISA Kit Customized Service Offer |