General Transcription Factor IIH, Polypeptide 5 (GTF2H5)
TTD; TFB5; TGF2H5; TTD-A; TTDA; DNA Repair Syndrome Trichothiodystrophy Group A
 HGNC 21157
 MGI 107227
 PubMed 15220921
 RGD 1560991
 UniProt Q6ZYL4
 USCN D900
 Wiki GTF2H5
General Transcription Factor IIH, Polypeptide 5 (GTF2H5)
General Transcription Factor IIH,Polypeptide 5 is a subunit of transcription/repair factor TFIIH, which functions in gene transcription and DNA repair. This protein stimulates ERCC3/XPB ATPase activity to trigger DNA opening during DNA repair, and is implicated in regulating cellular levels of TFIIH. Mutations in this gene result in trichothiodystrophy, complementation group A.
This protein, called TFB5, is a core component of yeast general transcription and DNA repair factor IIH (TFIIH). Database screening identified a human homolog of 71 amino acids that shares 28% identity with the yeast protein. Giglia-Mari et al. (2004) cloned the human cDNA corresponding to the TFB5 gene from primary fibroblasts.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a