Galactosylceramidase (GALC)
Galactocerebrosidase; Krabbe Disease
 HGNC 4115
 MGI 95636
 PubMed 14572137
 RGD 1359384
 UniProt P54803
 USCN G608
 Wiki GALC
Galactosylceramidase (GALC)
Galactosylceramidase (EC 3.2.1.46) is a lysosomal enzyme involved in the catabolism of galactosylceramide, a major lipid in myelin, kidney, and epithelial cells of the small intestine and colon.
Two overlapping clones containing the total protein coding region were obtained. The open reading frame codes for 669 amino acids, representing a protein with a molecular mass of approximately 73 kD.The cDNA encodes a single chain peptide with a 26-amino acid N-terminal signal peptide and 6 potential asparagine-linked glycosylation sites.The gene organization was nearly identical to that of the human gene, and the deduced amino acid sequence of monkey GALC was about 97%, 87%, and 83% identical to that in human, dog, and mouse, respectively.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG608Hu01 Recombinant Galactosylceramidase (GALC) SDS-PAGE; WB; ELISA; IP.
Antibodies PAG608Hu01 Polyclonal Antibody to Galactosylceramidase (GALC) WB, ICC, IHC-P, IHC-F, ELISA
PAG608Hu71 Biotin-Linked Antibody to Galactosylceramidase (GALC) IHC;WB;ELISA
Assay Kits n/a n/a n/a
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG608Ra01 Recombinant Galactosylceramidase (GALC) SDS-PAGE; WB; ELISA; IP.
Antibodies PAG608Ra01 Polyclonal Antibody to Galactosylceramidase (GALC) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits n/a n/a n/a