Galactosylceramidase (GALC)
Galactocerebrosidase; Krabbe Disease; Galactocerebroside beta-galactosidase; Galactosylceramidase; Galactosylceramide beta-galactosidase
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Galactosylceramidase (EC 3.2.1.46) is a lysosomal enzyme involved in the catabolism of galactosylceramide, a major lipid in myelin, kidney, and epithelial cells of the small intestine and colon.
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Two overlapping clones containing the total protein coding region were obtained. The open reading frame codes for 669 amino acids, representing a protein with a molecular mass of approximately 73 kD.The cDNA encodes a single chain peptide with a 26-amino acid N-terminal signal peptide and 6 potential asparagine-linked glycosylation sites.The gene organization was nearly identical to that of the human gene, and the deduced amino acid sequence of monkey GALC was about 97%, 87%, and 83% identical to that in human, dog, and mouse, respectively.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPG608Hu01 | Recombinant Galactosylceramidase (GALC) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAG608Hu01 | Polyclonal Antibody to Galactosylceramidase (GALC) | WB; IHC; ICC; IP. |
LAG608Hu71 | Biotin-Linked Polyclonal Antibody to Galactosylceramidase (GALC) | WB; IHC; ICC. | |
Assay Kits | SEG608Hu | ELISA Kit for Galactosylceramidase (GALC) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Galactosylceramidase (GALC) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Galactosylceramidase (GALC) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Galactosylceramidase (GALC) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Galactosylceramidase (GALC) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Galactosylceramidase (GALC) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPG608Ra01 | Recombinant Galactosylceramidase (GALC) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAG608Ra01 | Polyclonal Antibody to Galactosylceramidase (GALC) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for Galactosylceramidase (GALC) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Galactosylceramidase (GALC) | ELISA Kit Customized Service Offer |