GM2 Ganglioside Activator (GM2A)
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SAP-3; Cerebroside Sulfate Activator Protein; Sphingolipid Activator Protein 3
 HGNC 4367
 MGI 95762
 PubMed 11339652
 RGD 628651
 UniProt P17900
 USCN L122
 Wiki GM2A
GM2 Ganglioside Activator (GM2A)
GM2A is a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme β-hexosaminidase A. β-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines.
GM2A is a lipid transfer protein that stimulates the enzymatic processing of gangliosides, and also T-cell activation through lipid presentation. This protein binds molecules of ganglioside GM2, extracts them from membranes, and presents them to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.It was identified as a member of ML domain family of proteins involved in innate immunity and lipid metabolism in the SMART database.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPL122Hu01 Recombinant GM2 Ganglioside Activator (GM2A) SDS-PAGE; WB; ELISA; IP.
Antibodies MAL122Hu21 Monoclonal Antibody to GM2 Ganglioside Activator (GM2A) WB, ICC, IHC-P, IHC-F, ELISA
PAL122Hu01 Polyclonal Antibody to GM2 Ganglioside Activator (GM2A) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEL122Hu ELISA Kit for GM2 Ganglioside Activator (GM2A) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a