GATA Binding Protein 3 (GATA3)
HDR; Trans-acting T-cell-specific transcription factor GATA-3
Marine and Winoto (1991) identified a common TCR regulatory element by demonstrating binding of the enhancer-binding protein GATA3 to the enhancer elements of all 4 TCR genes. GATA3 had been shown in the chicken to be an enhancer-binding protein containing a zinc finger domain. GATA3 mRNA was demonstrated by Northern blot analysis in T cells but not in B cells, macrophages, or HeLa cell lines. GATA3 was abundantly expressed in the T-lymphocyte lineage and was thought to participate in T-cell receptor gene activation through binding to enhancers. Labastie et al. (1994) cloned the human gene and the 5-prime end of the mouse gene. The 2 zinc fingers of GATA3 are encoded by 2 separate exons highly conserved with those of GATA1, but no other structural homologies between the 2 genes could be found.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA410Hu01 | Recombinant GATA Binding Protein 3 (GATA3) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA410Hu01 | Polyclonal Antibody to GATA Binding Protein 3 (GATA3) | WB; IHC; ICC; IP. |
MAA410Hu22 | Monoclonal Antibody to GATA Binding Protein 3 (GATA3) | WB; IHC; ICC; IP. | |
MAA410Hu21 | Monoclonal Antibody to GATA Binding Protein 3 (GATA3) | WB; IHC; ICC; IP. | |
MAA410Hu23 | Monoclonal Antibody to GATA Binding Protein 3 (GATA3) | WB; IHC; ICC; IP. | |
MAA410Hu24 | Monoclonal Antibody to GATA Binding Protein 3 (GATA3) | WB; IHC; ICC; IP. | |
Assay Kits | SEA410Hu | ELISA Kit for GATA Binding Protein 3 (GATA3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant GATA Binding Protein 3 (GATA3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to GATA Binding Protein 3 (GATA3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to GATA Binding Protein 3 (GATA3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | SEA410Mu | ELISA Kit for GATA Binding Protein 3 (GATA3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant GATA Binding Protein 3 (GATA3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to GATA Binding Protein 3 (GATA3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to GATA Binding Protein 3 (GATA3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for GATA Binding Protein 3 (GATA3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for GATA Binding Protein 3 (GATA3) | ELISA Kit Customized Service Offer |