Fusion (FUS)
CHOP; ALS6; FUS-CHOP; FUS1; TLS; hnRNP-P2; RNA-Binding Protein FUS; Amyotrophic Lateral Sclerosis 6; Heterogeneous Nuclear Ribonucleoprotein P2
 HGNC 4010
 MGI 1353633
 RGD 1308864
 UniProt P35637
 USCN C260
Fusion (FUS)
FUS is a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. The N-terminal end of FUS appears to be involved in transcriptional activation, while the C-terminal end is involved in protein and RNA binding. In addition recognition sites for the transcription factors AP2, GCF, Sp1 have been identified in FUS.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC260Hu01 Recombinant Fusion (FUS) SDS-PAGE; WB; ELISA; IP.
Antibodies MAC260Hu22 Monoclonal Antibody to Fusion (FUS) WB, ICC, IHC-P, IHC-F, ELISA
PAC260Hu01 Polyclonal Antibody to Fusion (FUS) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEC260Hu ELISA Kit for Fusion (FUS) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC260Mu01 Recombinant Fusion (FUS) SDS-PAGE; WB; ELISA; IP.
RPC260Mu02 Recombinant Fusion (FUS) SDS-PAGE; WB; ELISA; IP.
Antibodies PAC260Mu01 Polyclonal Antibody to Fusion (FUS) WB, ICC, IHC-P, IHC-F, ELISA
PAC260Mu02 Polyclonal Antibody to Fusion (FUS) IWB, ICC, IHC-P, IHC-F, ELISA
PAC260Mu71 Biotin-Linked Antibody to Fusion (FUS) IHC;WB;ELISA
PAC260Mu81 FITC-Linked Antibody to Fusion (FUS) IHC;ICC;IF;WB
Assay Kits SEC260Mu ELISA Kit for Fusion (FUS) Enzyme-linked immunosorbent assay
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a