Furin (FUR)
PACE; PCSK3; SPC1; Paired Basic Amino Acid Cleaving Enzyme; Dibasic-processing enzyme
Furin is an enzyme which belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can efficiently cleave precursor proteins at their paired basic amino acid processing sites. Some of its substrates are: proparathyroid hormone, transforming growth factor beta 1 precursor, proalbumin, pro-beta-secretase, membrane type-1 matrix metalloproteinase, beta subunit of pro-nerve growth factor and von Willebrand factor. A furin-like pro-protein convertase has been implicated in the processing of RGMc (also called hemojuvelin ), a gene involved in a severe iron-overload disorder called juvenile hemochromatosis.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPC494Hu01 | Recombinant Furin (FUR) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPC494Hu02 | Recombinant Furin (FUR) | Positive Control; Immunogen; SDS-PAGE; WB. | |
RPC494Hu03 | Recombinant Furin (FUR) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAC494Hu01 | Polyclonal Antibody to Furin (FUR) | WB; IHC; ICC; IP. |
MAC494Hu22 | Monoclonal Antibody to Furin (FUR) | WB; IHC; ICC; IP. | |
PAC494Hu02 | Polyclonal Antibody to Furin (FUR) | WB; IHC; ICC; IP. | |
LAC494Hu71 | Biotin-Linked Polyclonal Antibody to Furin (FUR) | WB; IHC; ICC. | |
PAC494Hu03 | Polyclonal Antibody to Furin (FUR) | WB; IHC; ICC; IP. | |
Assay Kits | SEC494Hu | ELISA Kit for Furin (FUR) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPC494Mu01 | Recombinant Furin (FUR) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPC494Mu02 | Recombinant Furin (FUR) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAC494Mu01 | Polyclonal Antibody to Furin (FUR) | WB; IHC; ICC; IP. |
LAC494Mu71 | Biotin-Linked Polyclonal Antibody to Furin (FUR) | WB; IHC; ICC. | |
PAC494Mu02 | Polyclonal Antibody to Furin (FUR) | WB; IHC; ICC; IP. | |
Assay Kits | n/a | CLIA Kit for Furin (FUR) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Furin (FUR) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPC494Ra01 | Recombinant Furin (FUR) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAC494Ra21 | Monoclonal Antibody to Furin (FUR) | WB; IHC; ICC; IP. |
PAC494Ra01 | Polyclonal Antibody to Furin (FUR) | WB; IHC; ICC; IP. | |
Assay Kits | SEC494Ra | ELISA Kit for Furin (FUR) | Enzyme-linked immunosorbent assay for Antigen Detection. |