Furin (FUR)

PACE; PCSK3; SPC1; Paired Basic Amino Acid Cleaving Enzyme; Dibasic-processing enzyme

Furin is an enzyme which belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can efficiently cleave precursor proteins at their paired basic amino acid processing sites. Some of its substrates are: proparathyroid hormone, transforming growth factor beta 1 precursor, proalbumin, pro-beta-secretase, membrane type-1 matrix metalloproteinase, beta subunit of pro-nerve growth factor and von Willebrand factor. A furin-like pro-protein convertase has been implicated in the processing of RGMc (also called hemojuvelin ), a gene involved in a severe iron-overload disorder called juvenile hemochromatosis.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC494Hu01 Recombinant Furin (FUR) Positive Control; Immunogen; SDS-PAGE; WB.
RPC494Hu02 Recombinant Furin (FUR) Positive Control; Immunogen; SDS-PAGE; WB.
RPC494Hu03 Recombinant Furin (FUR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC494Hu01 Polyclonal Antibody to Furin (FUR) WB; IHC; ICC; IP.
MAC494Hu22 Monoclonal Antibody to Furin (FUR) WB; IHC; ICC; IP.
PAC494Hu02 Polyclonal Antibody to Furin (FUR) WB; IHC; ICC; IP.
LAC494Hu71 Biotin-Linked Polyclonal Antibody to Furin (FUR) WB; IHC; ICC.
PAC494Hu03 Polyclonal Antibody to Furin (FUR) WB; IHC; ICC; IP.
Assay Kits SEC494Hu ELISA Kit for Furin (FUR) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC494Mu01 Recombinant Furin (FUR) Positive Control; Immunogen; SDS-PAGE; WB.
RPC494Mu02 Recombinant Furin (FUR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC494Mu01 Polyclonal Antibody to Furin (FUR) WB; IHC; ICC; IP.
LAC494Mu71 Biotin-Linked Polyclonal Antibody to Furin (FUR) WB; IHC; ICC.
PAC494Mu02 Polyclonal Antibody to Furin (FUR) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Furin (FUR) CLIA Kit Customized Service Offer
n/a ELISA Kit for Furin (FUR) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC494Ra01 Recombinant Furin (FUR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAC494Ra21 Monoclonal Antibody to Furin (FUR) WB; IHC; ICC; IP.
PAC494Ra01 Polyclonal Antibody to Furin (FUR) WB; IHC; ICC; IP.
Assay Kits SEC494Ra ELISA Kit for Furin (FUR) Enzyme-linked immunosorbent assay for Antigen Detection.