Fucosyltransferase 6 (FUT6)
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FT1A; FCT3A; FucT-VI; Alpha-(1,3)-Fucosyltransferase; Galactoside 3-L-Fucosyltransferase
 HGNC 4017
 PubMed 1520296
 UniProt P51993
 USCN F196
 Wiki FUT6
Fucosyltransferase 6 (FUT6)
The alpha-1,3-fucosyltransferases constitute a large family of glycosyltransferases with a high degree of homology. The enzymes of this family comprise 3 main activity patterns called myeloid, plasma, and Lewis, based on their capacity to transfer alpha-L-fucose to distinct oligosaccharide acceptors, their sensitivity to N-ethylmaleimide inhibition, their cation requirements, and their tissue-specific expression patterns. The different categories of alpha-1,3-fucosyltransferases are sequentially expressed during embryo-fetal development. Transfection of FUT6 cDNA into mammalian cells conferred alpha-1,3-fucosyltransferase activity to the cells, resulting in cell surface expression of Lewis x and sialyl-Lewis x carbohydrates. Antibodies raised against another epitope of FUT6 localized the enzyme to Weibel-Palade bodies, endothelial storage granules.
Organism species: Homo sapiens (Human)
Proteins RPF196Hu01 Recombinant Fucosyltransferase 6 (FUT6) SDS-PAGE; WB; ELISA; IP.
Antibodies MAF196Hu21 Monoclonal Antibody to Fucosyltransferase 6 (FUT6) WB, ICC, IHC-P, IHC-F, ELISA
PAF196Hu01 Polyclonal Antibody to Fucosyltransferase 6 (FUT6) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEF196Hu ELISA Kit for Fucosyltransferase 6 (FUT6) Enzyme-linked immunosorbent assay