Fucosyltransferase 6 (FUT6)

FT1A; FCT3A; FucT-VI; Alpha-(1,3)-Fucosyltransferase; Galactoside 3-L-Fucosyltransferase

The alpha-1,3-fucosyltransferases constitute a large family of glycosyltransferases with a high degree of homology. The enzymes of this family comprise 3 main activity patterns called myeloid, plasma, and Lewis, based on their capacity to transfer alpha-L-fucose to distinct oligosaccharide acceptors, their sensitivity to N-ethylmaleimide inhibition, their cation requirements, and their tissue-specific expression patterns. The different categories of alpha-1,3-fucosyltransferases are sequentially expressed during embryo-fetal development. Transfection of FUT6 cDNA into mammalian cells conferred alpha-1,3-fucosyltransferase activity to the cells, resulting in cell surface expression of Lewis x and sialyl-Lewis x carbohydrates. Antibodies raised against another epitope of FUT6 localized the enzyme to Weibel-Palade bodies, endothelial storage granules.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF196Hu01 Recombinant Fucosyltransferase 6 (FUT6) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAF196Hu01 Polyclonal Antibody to Fucosyltransferase 6 (FUT6) WB; IHC; ICC; IP.
MAF196Hu21 Monoclonal Antibody to Fucosyltransferase 6 (FUT6) WB; IHC; ICC; IP.
Assay Kits SEF196Hu ELISA Kit for Fucosyltransferase 6 (FUT6) Enzyme-linked immunosorbent assay for Antigen Detection.