Frataxin (FXN)
FA; CyaY; FARR; FRDA; X25; Friedreich Ataxia
 HGNC 3951
 MGI 1096879
 PubMed 16911956
 RGD 1565754
 UniProt Q16595
 USCN C493
 Wiki Frataxin
Frataxin (FXN)
Frataxin is a small protein, localized to the mitochondrion. The function of frataxin is not entirely clear, but it seems to be involved in assembly of iron-sulfur clusters. It has been proposed to act as either an iron Chaperone (protein) or an iron storage protein.Reduced expression of frataxin is the cause of Friedrich's ataxia (FRDA), a lethal neurodegenerative disease.
This nuclear gene encodes a mitochondrial protein which belongs to FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC493Hu01 Recombinant Frataxin (FXN) SDS-PAGE; WB; ELISA; IP.
Antibodies PAC493Hu01 Polyclonal Antibody to Frataxin (FXN) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits n/a n/a n/a
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC493Mu01 Recombinant Frataxin (FXN) SDS-PAGE; WB; ELISA; IP.
RPC493Mu02 Recombinant Frataxin (FXN) SDS-PAGE; WB; ELISA; IP.
Antibodies PAC493Mu01 Polyclonal Antibody to Frataxin (FXN) IWB, ICC, IHC-P, IHC-F, ELISA
PAC493Mu02 Polyclonal Antibody to Frataxin (FXN) IWB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEC493Mu ELISA Kit for Frataxin (FXN) Enzyme-linked immunosorbent assay
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a