Family With Sequence Similarity 20, Member C (FAM20C)
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DMP4; Dentin Matrix Protein 4
 HGNC 22140
 MGI 2136853
 PubMed 22615579
 RGD 1311980
 UniProt Q8IXL6
 USCN K373
 Wiki FAM20C
Family With Sequence Similarity 20, Member C (FAM20C)
DMP4 (FAM20C), from a rat odontoblast cDNA library. Using a partial rat DMP4 sequence, they obtained a full-length mouse Dmp4 cDNA, which encodes a deduced 579-amino acid protein with a 26-amino acid signal sequence, a Greek key calcium-binding domain, and a conserved C-terminal domain. The protein contains several potential N-linked glycosylation sites and has a calculated pI of 7.1, much different from other dentin matrix proteins, which are acidic. Northern blot analysis of mouse tissues showed highest levels of transcript in the dental pulp-odontoblast complex, moderate expression in bone, and low expression in kidney, liver, brain, and lung. Transfection experiments demonstrated perinuclear and cytoplasmic staining, consistent with an endoplasmic reticulum localization.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a