Ewing Sarcoma Breakpoint Region 1 (EWSR1)
EWS; RNA-binding protein EWS; EWS oncogene
EWSR1 encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11;22)(q24;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Ewing Sarcoma Breakpoint Region 1 (EWSR1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Ewing Sarcoma Breakpoint Region 1 (EWSR1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Ewing Sarcoma Breakpoint Region 1 (EWSR1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Ewing Sarcoma Breakpoint Region 1 (EWSR1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Ewing Sarcoma Breakpoint Region 1 (EWSR1) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Ewing Sarcoma Breakpoint Region 1 (EWSR1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Ewing Sarcoma Breakpoint Region 1 (EWSR1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Ewing Sarcoma Breakpoint Region 1 (EWSR1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Ewing Sarcoma Breakpoint Region 1 (EWSR1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Ewing Sarcoma Breakpoint Region 1 (EWSR1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Ewing Sarcoma Breakpoint Region 1 (EWSR1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Ewing Sarcoma Breakpoint Region 1 (EWSR1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Ewing Sarcoma Breakpoint Region 1 (EWSR1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Ewing Sarcoma Breakpoint Region 1 (EWSR1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Ewing Sarcoma Breakpoint Region 1 (EWSR1) | ELISA Kit Customized Service Offer |