Ets Variant 6 (ETV6)
TEL; TEL/ABL
 HGNC 3495
 MGI 109336
 RGD 1559537
 UniProt P41212
 USCN J726
Ets Variant 6 (ETV6)
ETV6 encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in the protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.
Portions of the gene showed homology to the ETS family of transcription factors, and it was designated 'TEL' for translocation, ETS, leukemia. Northern blot analysis detected 3 transcripts of 6.5 kb, 4.5 kb, and 2.4 kb in all tissues examined.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a