Engrailed Homeobox Protein 2 (EN2)
AUTS1
 HGNC 3343
 MGI 95390
 PubMed 21364037
 RGD 1561842
 UniProt P19622
 USCN J982
 Wiki EN2
Engrailed Homeobox Protein 2 (EN2)
Prostate cancer (PC) is the second most common cause of cancer related death in men. A number of key limitations with prostate specific antigen (PSA), currently the standard detection test, has justified evaluation of new biomarkers.Engrailed-2 (EN2) protein, a homeodomain-containing transcription factor expressed in PC cell lines and secreted into the urine by PC in men. EN2 was expressed and secreted by PC cell lines and PC tissue but not by normal prostate tissue or stroma. The presence of EN2 in urine was highly predictive of PC, with a sensitivity of 66% and a specificity of 88.2%, without requirement for DRE. There was no correlation with PSA levels.Urinary EN2 is a highly specific and sensitive candidate biomarker of prostate cancer.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPJ982Hu01 Recombinant Engrailed Homeobox Protein 2 (EN2) SDS-PAGE; WB; ELISA; IP.
Antibodies MAJ982Hu21 Monoclonal Antibody to Engrailed Homeobox Protein 2 (EN2) WB, ICC, IHC-P, IHC-F, ELISA
PAJ982Hu01 Polyclonal Antibody to Engrailed Homeobox Protein 2 (EN2) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEJ982Hu ELISA Kit for Engrailed Homeobox Protein 2 (EN2) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a