Endothelin Converting Enzyme 1 (ECE1)
 HGNC 3146
 MGI 1101357
 OMIM 600423
 RGD 620293
 UCSC uc001bei.2
 UniProt P42892
 USCN 90483
Endothelin Converting Enzyme 1 (ECE1)
Endothelin converting enzyme 1, also known as ECE1, is a enzyme which in humans is encoded by the ECE1 gene.Endothelin-converting enzyme-1 is involved in the proteolytic processing of endothelin-1 (EDN1), -2 (EDN2), and -3 (EDN3) to biologically active peptides.
Schmidt et al. (1994) purified a membrane-bound protease activity from bovine endothelial cells that specifically converts the inactive form to EDN1. The enzyme was cleaved with trypsin and peptide sequencing analysis confirmed it to be a zinc-chelating metalloprotease containing the typical HEXXH (HELTH) motif. RT-PCR and cDNA screens were used to isolate the complete cDNAs of the bovine and human enzymes.
 ELISA Kits(Enzyme-linked immunosorbent assay Kits)
Catalog Product Name Organism Manual
E90483HuELISA Kit for Endothelin Converting Enzyme 1 (ECE1)Homo sapiens (Human)  PDF
E90483MuELISA Kit for Endothelin Converting Enzyme 1 (ECE1)Mus musculus (Mouse)  PDF
E90483RaELISA Kit for Endothelin Converting Enzyme 1 (ECE1)Rattus norvegicus (Rat)  n/a
 CLIA Kits(Chemiluminescent immunoassay Kits)
Catalog Product Name Organism Manual
C90483HuCLIA Kit for Endothelin Converting Enzyme 1 (ECE1)Homo sapiens (Human)  n/a
C90483MuCLIA Kit for Endothelin Converting Enzyme 1 (ECE1)Mus musculus (Mouse)  n/a
C90483RaCLIA Kit for Endothelin Converting Enzyme 1 (ECE1)Rattus norvegicus (Rat)  n/a