Endothelin Converting Enzyme 1(ECE1)
 H U G O 3146
M   G   I 1101357
O M I M 600423
R   G   D 620293
U C S C uc001bei.2
UniProt P42892
USCNK 90483
Endothelin Converting Enzyme 1(ECE1)
Endothelin converting enzyme 1, also known as ECE1, is a enzyme which in humans is encoded by the ECE1 gene.Endothelin-converting enzyme-1 is involved in the proteolytic processing of endothelin-1 (EDN1), -2 (EDN2), and -3 (EDN3) to biologically active peptides.
Schmidt et al. (1994) purified a membrane-bound protease activity from bovine endothelial cells that specifically converts the inactive form to EDN1. The enzyme was cleaved with trypsin and peptide sequencing analysis confirmed it to be a zinc-chelating metalloprotease containing the typical HEXXH (HELTH) motif. RT-PCR and cDNA screens were used to isolate the complete cDNAs of the bovine and human enzymes.
 ELISA Kits(Enzyme-linked immunosorbent assay Kits)
Catalog Product Name Species Packing Price Manual
E90483HuELISA Kit for Human Endothelin Converting Enzyme 1(ECE1)Human96T$700   n/a
E90483MuELISA Kit for Mouse Endothelin Converting Enzyme 1(ECE1)Mouse96T$720   PDF
E90483RaELISA Kit for Rat Endothelin Converting Enzyme 1(ECE1)Rat96T$760   n/a
 Antibodies
Catalog Product Name Species Packing Price Manual
A90483HuAntibody to Human Endothelin Converting Enzyme 1(ECE1)Humann/an/a   n/a
A90483MuAntibody to Mouse Endothelin Converting Enzyme 1(ECE1)Mousen/an/a   n/a
A90483RaAntibody to Rat Endothelin Converting Enzyme 1(ECE1)Ratn/an/a   n/a
 CLIA Kits(Chemiluminescent immunoassay Kits)
Catalog Product Name Species Packing Price Manual
C90483HuCLIA Kit for Human Endothelin Converting Enzyme 1(ECE1)Humann/an/a   n/a
C90483MuCLIA Kit for Mouse Endothelin Converting Enzyme 1(ECE1)Mousen/an/a   n/a
C90483RaCLIA Kit for Rat Endothelin Converting Enzyme 1(ECE1)Ratn/an/a   n/a