ELAV Like Protein 1 (ELAVL1)
ELAV1; HUR; Hua; MelG; Hu Antigen R; Embryonic Lethal,Abnormal Vision Like 1
 HGNC 3312
 MGI 1100851
 PubMed 21737689
 RGD 1308649
 UniProt Q15717
 USCN J780
 Wiki ELAVL1
ELAV Like Protein 1 (ELAVL1)
ELAVL1 is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It stabilizes mRNAs and thereby regulates gene expression.Like other ELAVL proteins, HuR has a short N-terminal region followed by 2 RNA-binding motifs, a basic linker domain, and a third RNA-binding motif. HuR was expressed ubiquitously, in contrast to the neural-specific expression of ELAVL2, ELAVL3, and ELAVL4.HuR associated with SIRT1 mRNA and enhanced its stability. In human diploid fibroblasts, they found a concomitant reduction in both HuR and SIRT1 during replicative senescence. Oxidative stress lowered SIRT1 mRNA and protein levels, caused the dissociation of HuR from SIRT1 mRNA, and reduced the stability of SIRT1 mRNA in an HuR-dependent manner.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPJ780Ra01 Recombinant ELAV Like Protein 1 (ELAVL1) SDS-PAGE; WB; ELISA; IP.
Antibodies MAJ780Ra21 Monoclonal Antibody to ELAV Like Protein 1 (ELAVL1) WB, ICC, IHC-P, IHC-F, ELISA
PAJ780Ra01 Polyclonal Antibody to ELAV Like Protein 1 (ELAVL1) IWB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEJ780Ra ELISA Kit for ELAV Like Protein 1 (ELAVL1) Enzyme-linked immunosorbent assay