EEN Binding Protein (EBP)
SH3D19; EVE1; Kryn; SH3P19; SH3 Domain Containing 19; ADAM-binding protein Eve-1
The deduced 767-amino acid protein has a central proline-rich region and 4 C-terminal SH3 domains. PCR analysis detected EBP expression in all adult and fetal tissues examined. Epitope-tagged EBP was evenly distributed in the cytoplasm of transfected HeLa cells.
EBP was recruited to the nucleus by the chimeric MLL-EEN fusion protein. The SH3 domains of EBP interacted with SOS2, but not SOS1, and that the EBP-EEN and EBP-SOS2 interactions occurred simultaneously. Coexpression of EBP with EEN in rat embryonic fibroblasts led to suppression of RAS -induced cellular transformation and RAS-mediated activation of ELK1 .
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant EEN Binding Protein (EBP) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to EEN Binding Protein (EBP) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to EEN Binding Protein (EBP) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for EEN Binding Protein (EBP) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for EEN Binding Protein (EBP) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant EEN Binding Protein (EBP) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to EEN Binding Protein (EBP) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to EEN Binding Protein (EBP) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for EEN Binding Protein (EBP) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for EEN Binding Protein (EBP) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant EEN Binding Protein (EBP) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to EEN Binding Protein (EBP) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to EEN Binding Protein (EBP) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for EEN Binding Protein (EBP) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for EEN Binding Protein (EBP) | ELISA Kit Customized Service Offer |