EEN Binding Protein (EBP)

SH3D19; EVE1; Kryn; SH3P19; SH3 Domain Containing 19; ADAM-binding protein Eve-1

The deduced 767-amino acid protein has a central proline-rich region and 4 C-terminal SH3 domains. PCR analysis detected EBP expression in all adult and fetal tissues examined. Epitope-tagged EBP was evenly distributed in the cytoplasm of transfected HeLa cells.
EBP was recruited to the nucleus by the chimeric MLL-EEN fusion protein. The SH3 domains of EBP interacted with SOS2, but not SOS1, and that the EBP-EEN and EBP-SOS2 interactions occurred simultaneously. Coexpression of EBP with EEN in rat embryonic fibroblasts led to suppression of RAS -induced cellular transformation and RAS-mediated activation of ELK1 .

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant EEN Binding Protein (EBP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to EEN Binding Protein (EBP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to EEN Binding Protein (EBP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for EEN Binding Protein (EBP) CLIA Kit Customized Service Offer
n/a ELISA Kit for EEN Binding Protein (EBP) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant EEN Binding Protein (EBP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to EEN Binding Protein (EBP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to EEN Binding Protein (EBP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for EEN Binding Protein (EBP) CLIA Kit Customized Service Offer
n/a ELISA Kit for EEN Binding Protein (EBP) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant EEN Binding Protein (EBP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to EEN Binding Protein (EBP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to EEN Binding Protein (EBP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for EEN Binding Protein (EBP) CLIA Kit Customized Service Offer
n/a ELISA Kit for EEN Binding Protein (EBP) ELISA Kit Customized Service Offer