Docking Protein 7 (DOK7)
C4orf25; Downstream of tyrosine kinase 7
DOK7 is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants. DOK7 contains a pleckstrin homology (PH) and PTB domain in the N-terminal portion and Src homology 2 (SH2) domain target motifs in the C-terminal region. Cloning of mouse and pufferfish Dok7 cDNA revealed a highly conserved structure.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Docking Protein 7 (DOK7) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Docking Protein 7 (DOK7) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Docking Protein 7 (DOK7) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Docking Protein 7 (DOK7) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Docking Protein 7 (DOK7) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Docking Protein 7 (DOK7) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Docking Protein 7 (DOK7) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Docking Protein 7 (DOK7) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Docking Protein 7 (DOK7) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Docking Protein 7 (DOK7) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPF377Ra01 | Recombinant Docking Protein 7 (DOK7) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAF377Ra01 | Polyclonal Antibody to Docking Protein 7 (DOK7) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for Docking Protein 7 (DOK7) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Docking Protein 7 (DOK7) | ELISA Kit Customized Service Offer |