Dihydrolipoyl Transacetylase (DLAT)
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DLTA; PDC-E2; Dihydrolipoamide Acetyltransferase; Dihydrolipoamide S-Acetyltransferase; E2 Component Of Pyruvate Dehydrogenase Complex
 HGNC 2896
 MGI 2385311
 PubMed 7487063
 RGD 619859
 UniProt P10515
 USCN A696
 Wiki DLAT
Dihydrolipoyl Transacetylase (DLAT)
Dihydrolipoyl transacetylase is the component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC). PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A. The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A. Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC enventually leads to cirrhosis and liver failure.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA696Hu01 Recombinant Dihydrolipoyl Transacetylase (DLAT) SDS-PAGE; WB; ELISA; IP.
Antibodies PAA696Hu01 Polyclonal Antibody to Dihydrolipoyl Transacetylase (DLAT) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits n/a n/a n/a
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA696Mu01 Recombinant Dihydrolipoyl Transacetylase (DLAT) SDS-PAGE; WB; ELISA; IP.
RPA696Mu02 Recombinant Dihydrolipoyl Transacetylase (DLAT) SDS-PAGE; WB; ELISA; IP.
Antibodies PAA696Mu01 Polyclonal Antibody to Dihydrolipoyl Transacetylase (DLAT) WB, ICC, IHC-P, IHC-F, ELISA
PAA696Mu02 Polyclonal Antibody to Dihydrolipoyl Transacetylase (DLAT) IWB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEA696Mu ELISA Kit for Dihydrolipoyl Transacetylase (DLAT) Enzyme-linked immunosorbent assay
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Danio rerio (Zebrafish)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a